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用于练习 Descemet 膜内皮角膜移植术的人体离体前房模型

Human Ex Vivo Artificial Anterior Chamber Model for Practice DMEK Surgery.

作者信息

Vasquez Perez Alfonso, Liu Christopher

机构信息

Sussex Eye Hospital, Anterior Segment Department, Brighton and Sussex University Hospitals NHS, Brighton, United Kingdom.

出版信息

Cornea. 2017 Mar;36(3):394-397. doi: 10.1097/ICO.0000000000001112.

DOI:10.1097/ICO.0000000000001112
PMID:27984366
Abstract

PURPOSE

To describe a wet lab model using human corneas for practicing all steps of Descemet membrane endothelial keratoplasty (DMEK).

METHODS

Twelve human research corneas were used for training purposes. Each DMEK surgery required 2 corneas; one for donor graft preparation and one to practice graft insertion and unfolding in a novel artificial anterior chamber model.

RESULTS

Six complete DMEK procedures were successfully performed. Apart from donor graft preparation and graft insertion into the anterior chamber, it was feasible to practice different and combinations of graft unfolding techniques in conditions similar to real human procedures.

CONCLUSIONS

This wet lab model allows practicing steps of DMEK and learning significant surgical skills. Reusable instruments can be used in regular operating facilities resulting in reasonable costs.

摘要

目的

描述一种使用人角膜的湿实验室模型,用于练习Descemet膜内皮角膜移植术(DMEK)的所有步骤。

方法

使用12个人类研究角膜用于训练目的。每次DMEK手术需要2个角膜;一个用于供体移植物制备,另一个用于在新型人工前房模型中练习移植物植入和展开。

结果

成功完成了6例完整的DMEK手术。除了供体移植物制备和将移植物植入前房外,在类似于真实人类手术的条件下练习不同的移植物展开技术及其组合是可行的。

结论

这种湿实验室模型允许练习DMEK的步骤并学习重要的手术技能。可重复使用的器械可在常规手术设施中使用,成本合理。

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