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锁骨接骨术后骨不连:痤疮丙酸杆菌感染率高。

Nonunion After Clavicle Osteosynthesis: High Incidence of Propionibacterium acnes.

作者信息

Gausden Elizabeth B, Villa Jordan, Warner Stephen J, Redko Mariya, Pearle Andrew, Miller Andy, Henry Michael, Lorich Dean G, Helfet David L, Wellman David S

机构信息

*Hospital for Special Surgery, New York, NY; and †Department of Orthopaedic Surgery, Weill Cornell Medical College, New York, NY.

出版信息

J Orthop Trauma. 2017 Apr;31(4):229-235. doi: 10.1097/BOT.0000000000000770.

Abstract

OBJECTIVE

The objective of this study was to review the etiology of clavicle nonunions after osteosynthesis and investigate the outcomes of a treatment with a single-stage revision.

DESIGN

Retrospective case series.

SETTING

Orthopaedic specialty hospital.

PATIENTS

Twenty cases of nonunion after osteosynthesis of the clavicle were identified. The average age was 44 years (±13 years). In 9 cases, there was catastrophic implant failure that prompted the revision surgery. In the 18 cases in which cultures were taken, 15 of the 18 (83%) were treated as infections with a course of antibiotics. In 14 cases, the cultures were positive for Propionibacterium acnes.

RESULTS

Fifteen patients were treated with a prolonged course of antibiotics. Eighteen patients had follow-up, and the average time to radiographic union was 22 weeks. There were no cases of nonunion after revision surgery.

CONCLUSIONS

There is a high rate of positive cultures in cases of nonunion after osteosynthesis of the clavicle. This suggests the etiology of midshaft clavicle nonunions may result from a combination of suboptimal mechanical fixation and latent infection. Our treatment protocol of superior and anterior plating, interfragmentary fixation, bone grafting, and appropriate antimicrobial treatment of latent infections has resulted in 100% union rate.

LEVEL OF EVIDENCE

Prognostic Level IV. See Instructions for Authors for a complete description of levels of evidence.

摘要

目的

本研究的目的是回顾锁骨接骨术后骨不连的病因,并探讨一期翻修治疗的效果。

设计

回顾性病例系列研究。

地点

骨科专科医院。

患者

确定了20例锁骨接骨术后骨不连病例。平均年龄为44岁(±13岁)。9例出现灾难性内固定失败,促使进行翻修手术。在18例进行培养的病例中,18例中的15例(83%)被当作感染病例给予抗生素疗程治疗。14例培养结果显示痤疮丙酸杆菌呈阳性。

结果

15例患者接受了延长疗程的抗生素治疗。18例患者进行了随访,影像学显示骨愈合的平均时间为22周。翻修手术后无骨不连病例。

结论

锁骨接骨术后骨不连病例中培养阳性率很高。这表明锁骨中段骨不连的病因可能是机械固定欠佳和潜在感染共同作用的结果。我们采用的上方和前方钢板固定、骨折块间固定、植骨以及对潜在感染进行适当抗菌治疗的治疗方案,使骨愈合率达到了100%。

证据水平

预后IV级。有关证据水平的完整描述,请参阅《作者须知》。

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