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浅静脉解剖结构不佳患者的肱动脉-肱静脉动静脉内瘘与动静脉移植物的比较。

A comparison of brachial artery-brachial vein arteriovenous fistulas with arteriovenous grafts in patients with poor superficial venous anatomy.

作者信息

Pham Xuan-Binh D, Kim Jerry J, Ihenachor Ezinne J, Parrish Aaron B, Bleck Jenny D, Kaji Amy H, Koopmann Matthew C, de Virgilio Christian

机构信息

Department of Surgery, Harbor-University of California, Los Angeles (UCLA) Medical Center, Torrance, Calif.

The David Geffen School of Medicine at UCLA, Los Angeles, Calif.

出版信息

J Vasc Surg. 2017 Feb;65(2):444-451. doi: 10.1016/j.jvs.2016.09.037. Epub 2016 Dec 13.

Abstract

OBJECTIVE

The autogenous arteriovenous fistula (AVF) has been shown to be superior to the arteriovenous graft (AVG) with respect to cost, complications, and primary patency. Therefore, the National Kidney Foundation Disease Outcomes Quality Initiative guidelines recommend reserving AVGs for patients who do not have adequate superficial venous anatomy to support AVF placement. The brachial artery-brachial vein arteriovenous fistula (BVAVF) has emerged as an autologous last-effort alternative. However, there are limited data comparing BVAVFs and AVGs in patients who are otherwise not candidates for a traditional AVF.

METHODS

Patients who received a BVAVF from July 2009 to July 2014 were compared with those who received an AVG during the same period. At our institution, BVAVF and AVG are only performed in patients with poor superficial venous anatomy. Patient demographic data, operative details, and subsequent follow-up were collected. BVAVFs were performed with a two-stage approach, with initial arteriovenous anastomosis, followed by delayed superficialization or transposition. Our primary outcome measure was primary functional assisted patency at 1 year. Patients lost to follow-up were excluded. A subgroup analysis was also performed for patients in whom the BVAVF or the AVG was their first hemodialysis access surgery.

RESULTS

During the study period, 29 patients underwent BVAVF and 32 underwent AVG. There were no differences in age, gender, or presence of diabetes between the two groups. The median days to cannulation from the initial operation were 141 (interquartile range, 94-214) in the BVAVF group and 29 (interquartile range, 14-33) in the AVG group (P < .001). Fewer patients required interventions to maintain or re-establish patency in the BVAVF group than in the AVG group (10% v. 44%; P < .01). The 1-year primary patency was greater for BVAVF (62% vs 25%; P < .01); however, there was no difference in the functional assisted primary patency rates at 1 year (45% vs 25%; P = .1). Subgroup analysis demonstrated greater 1-year primary functional assisted primary patency (52% vs 19%; P < .05) in patients without prior access surgery.

CONCLUSIONS

The BVAVF is a viable alternative to the AVG in patients with inadequate superficial venous anatomy, especially in access-naïve patients. The decision to perform BVAVF must be weighed against the delay in functional maturation expected compared with AVG.

摘要

目的

自体动静脉内瘘(AVF)在成本、并发症及初始通畅率方面已被证明优于动静脉移植物(AVG)。因此,美国国家肾脏基金会疾病预后质量倡议指南建议,对于没有足够表浅静脉解剖结构以支持AVF植入的患者,保留AVG作为选择。肱动脉-肱静脉动静脉内瘘(BVAVF)已成为一种自体的最后手段替代方案。然而,在那些不适合传统AVF的患者中,比较BVAVF和AVG的资料有限。

方法

将2009年7月至2014年7月期间接受BVAVF的患者与同期接受AVG的患者进行比较。在我们机构,BVAVF和AVG仅用于表浅静脉解剖结构不佳的患者。收集患者的人口统计学数据、手术细节及后续随访情况。BVAVF采用两阶段方法进行,首先进行动静脉吻合,随后进行延迟的表浅化或转位。我们的主要结局指标是1年时的初始功能辅助通畅率。失访患者被排除。还对首次接受BVAVF或AVG进行血液透析通路手术的患者进行了亚组分析。

结果

在研究期间,29例患者接受了BVAVF,32例患者接受了AVG。两组在年龄、性别或糖尿病患病率方面无差异。BVAVF组从初始手术到开始穿刺的中位天数为141天(四分位间距,94 - 214天),AVG组为29天(四分位间距,14 - 33天)(P < .001)。与AVG组相比,BVAVF组需要干预以维持或重建通畅的患者更少(10%对44%;P < .01)。BVAVF的1年初始通畅率更高(62%对25%;P < .01);然而,1年时的功能辅助初始通畅率无差异(45%对25%;P = .1)。亚组分析显示,未接受过通路手术的患者1年时的初始功能辅助通畅率更高(52%对19%;P < .05)。

结论

对于表浅静脉解剖结构不佳的患者,尤其是初次建立通路的患者,BVAVF是AVG的可行替代方案。决定进行BVAVF时,必须权衡与AVG相比预期的功能成熟延迟。

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