Velu Juliëtte F, de Boer Hans H, Bouma Berto J, Baan Jan
Department of Cardiology, Academic Medical Center, Amsterdam, The Netherlands.
Department of Pathology, Academic Medical Center, Amsterdam, The Netherlands.
J Heart Valve Dis. 2016 May;25(3):320-322.
A 73-year-old male received a percutaneous mitral valve repair with a MitraClip to treat severe (grade IV) symptomatic mitral regurgitation (MR). The MitraClip® procedure reduced the MR to grade I, but the patient died 14 days post-procedurally due to a pneumosepsis. Histological analysis of the MitraClip mesh covering showed a chronic inflammatory reaction with an abundance of multinucleated giant cells. Remarkably, signs of early onset clip-coverage were found, indicated by the presence of a few scattered myofibroblasts.
