Jánó Zoltán, Mohos Elemér, Réti György, Kovács Tamás, Mohay József, Berki Csaba, Horváth Sándor, Bene Krisztina, Horzov Myroslav, Bognár Gábor, Sándor Gábor, Szenkovits Péter, Mohos Petra, Tornai Gábor, Nagy Attila
Általános és Érsebészeti Centrum, Veszprém Megyei Csolnoky Ferenc Kórház 8200 Veszprém, Kórház u. 1.
Magy Seb. 2016 Dec;69(4):150-158. doi: 10.1556/1046.69.2016.4.2.
Albeit there is decreasing tendency nowadays for stoma construction, if it still happens, parastomal herniation might occur in up to 50% of cases afterwards. One third of the cases requires surgical correction, not rarely as an emergency. The different methods of repair can be quite demanding and the complication rates are high. From 2003 we have started to use specially designed 3-dimensional meshes for the prevention and repair of parastomal hernias.
From 1st of January 2012 to 1st of June 2016 we have used these devices within the framework of a prospective, controlled, randomized study enrolling the patients in preventive and repair arms. Until now mesh was implanted for prevention at the time of the index operation in 38 cases, (control group: 46 cases), and for repair in 14 cases (control group: 18 cases). Recruitment of the patients will end in 2017. The operations were performed by laparoscopic approach in 22 cases and by open approach in 62 cases in the preventive arm, and 6/26 cases in the repair arm respectively. Mean follow up period is 19.2 months in the mesh group and 22.6 months in the non mesh group in the preventive arm, and 25.9/20.4 months in the repair arm respectively.
No statistical analysis was used to interpret these interim results in this paper, we intend to analyze our results at the end of the study. At this stage apparently there is no difference between the group of patients in terms of complications in both arms. Parastomal herniation was found in 18 cases (39.1%) in the non mesh group and in 3 cases (7.8%) in the mesh group in the preventive arm. Recurrency was noted in 8 cases (44%) in the non mesh group, and in 1 case (7.1%) in the mesh group in the repair arm.
Our results correlate with other studies where mesh insertion was used to prevent and/or repair parastomal hernias. We attribute these results mainly to the special, 3-dimensional design of the meshes used by us. This construction was developed based on understanding the patomechanism of parastomal hernia formation.
尽管如今造口术的实施趋势有所下降,但如果仍需进行造口术,术后高达50%的病例可能会发生造口旁疝。三分之一的病例需要手术矫正,紧急情况并不少见。不同的修复方法要求颇高且并发症发生率很高。自2003年起,我们开始使用专门设计的三维网片来预防和修复造口旁疝。
从2012年1月1日至2016年6月1日,我们在一项前瞻性、对照、随机研究框架内使用了这些装置,该研究将患者分为预防组和修复组。截至目前,38例患者在初次手术时植入网片用于预防(对照组:46例),14例患者植入网片用于修复(对照组:18例)。患者招募将于2017年结束。预防组中,22例手术通过腹腔镜入路进行,62例通过开放入路进行,修复组中分别为6/26例。预防组中网片组的平均随访期为19.2个月,非网片组为22.6个月,修复组分别为25.9/20.4个月。
本文未使用统计分析来解读这些中期结果,我们打算在研究结束时分析结果。在此阶段,两组患者在并发症方面显然没有差异。预防组中非网片组有18例(39.1%)发生造口旁疝,网片组有3例(7.8%)。修复组中非网片组有8例(44%)复发,网片组有1例(7.1%)。
我们的结果与其他使用网片植入来预防和/或修复造口旁疝的研究结果相符。我们将这些结果主要归因于我们所使用网片的特殊三维设计。这种构造是基于对造口旁疝形成病理机制的理解而研发的。