[沉淀素在养鸟人肺诊断中的应用：附2例报告]

[Use of precipitins in the diagnosis of bird fancier's lung: apropos of 2 cases].

作者信息

Reynaud C, de Haller R, Ribaux C, Nerbollier G, Richardet C, Polla B S

机构信息

Département de médecine, Hôpital cantonal universitaire de Genève.

出版信息

Schweiz Med Wochenschr. 1989 Jul 22;119(29):1005-9.

PMID:2799327

Abstract

Bird breeder's disease is a frequent diagnosis among the forms of extrinsic allergic alveolitis seen in the urban environment. We report two illustrative cases and discuss the respective roles of broncho-alveolar lavage cells and precipitating antibodies against avian antigens in the diagnostic work-up and the pathogenesis of the disease. In 1988 we evaluated over 100 sera from all over Switzerland with clinical suspicion of bird breeder's disease. In this cohort preliminary results show sensitivity of 85% and specificity of 92% for the presence of precipitins against avian antigens in the diagnosis of bird breeder's disease. The results suggest that this non-invasive test deserves revaluation as a diagnostic tool in bird breeder's disease.

摘要

养鸟者病是城市环境中所见的外源性过敏性肺泡炎的常见诊断类型。我们报告两例说明性病例，并讨论支气管肺泡灌洗细胞和抗禽类抗原沉淀抗体在该病诊断检查及发病机制中的各自作用。1988年，我们对来自瑞士各地临床怀疑患有养鸟者病的100多份血清进行了评估。在这个队列中，初步结果显示，在养鸟者病的诊断中，针对禽类抗原的沉淀素检测的敏感性为85%，特异性为92%。结果表明，这项非侵入性检测作为养鸟者病的诊断工具值得重新评估。