Viidanoja Jyrki
Technology Centre, Neste Corporation, P.O. Box 310, FI-06101 Porvoo, Finland.
J Chromatogr A. 2017 Jan 13;1480:106-111. doi: 10.1016/j.chroma.2016.12.037. Epub 2016 Dec 15.
A new liquid chromatography-electrospray ionization-tandem Mass Spectrometry (LC-ESI-MS/MS) method was developed for the determination of more than 20 C-C alkyl and alkanolamines in aqueous matrices. The method employs Hydrophilic Interaction Liquid Chromatography Multiple Reaction Monitoring (HILIC-MRM) with a ZIC-pHILIC column and four stable isotope labeled amines as internal standards for signal normalization and quantification of the amines. The method was validated using a refinery process water sample that was obtained from a cooling cycle of crude oil distillation. The averaged within run precision, between run precision and accuracy were generally within 2-10%, 1-9% and 80-120%, respectively, depending on the analyte and concentration level. Selected aqueous process samples were analyzed with the method.
开发了一种新的液相色谱-电喷雾电离-串联质谱（LC-ESI-MS/MS）方法，用于测定水性基质中的20多种碳-碳烷基和链烷醇胺。该方法采用亲水相互作用液相色谱多反应监测（HILIC-MRM），使用ZIC-pHILIC柱和四种稳定同位素标记的胺作为内标，用于信号归一化和胺的定量。该方法通过从原油蒸馏冷却循环中获得的炼油厂工艺水样进行了验证。根据分析物和浓度水平，平均批内精密度、批间精密度和准确度通常分别在2-10%、1-9%和80-120%以内。使用该方法对选定的水性工艺样品进行了分析。
