Quadri F, Marone C
Dipartimento di Medicina interna, Ospedale San Giovanni, Bellinzona.
Schweiz Med Wochenschr. 1989 Oct 14;119(41):1434-6.
A 70-year-old patient with a history of rheumatoid arthritis was hospitalized for severe acute pneumonitis after 36 weeks of treatment with low-dose methotrexate (7.5 mg/week). High dose corticotherapy and assisted ventilation were necessary to obtain a clinical response. Medical history, clinical signs, laboratory findings. X-ray films of the chest and special investigations suggest the diagnosis of acute low-dose methotrexate pneumonitis.