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胆管癌和胆囊癌的现状

Current Status on Cholangiocarcinoma and Gallbladder Cancer.

作者信息

Ebata Tomoki, Ercolani Giorgio, Alvaro Domenico, Ribero Dario, Di Tommaso Luca, Valle Juan W

机构信息

Division of Surgical Oncology, Department of Surgery, Nagoya University Graduate School of Medicine, Nagoya, Japan.

Department of Medical and Surgical Sciences, Hospital Sant'orsola-Malpighi, University of Bologna, Bologna, Italy.

出版信息

Liver Cancer. 2016 Nov;6(1):59-65. doi: 10.1159/000449493. Epub 2016 Nov 29.

Abstract

BACKGROUND

Cholangiocarcinomas (CC) as well as gallbladder cancers are relatively rare and intractable diseases. Clinical, pathological, and epidemiological studies on these tumors have been under investigation. The current status and/or topics on biliary tract cancers have been reported in the East West Association of Liver Tumor (EWALT), held in Milano, Italy in 2015.

SUMMARY

All the authors, herein, specifcally reported the current status and leading-edge findings on biliary tract cancers as the following sequence: epidemiology of CC, surgical therapy for intrahepatic CC, surgical therapy for perihilar CC, surgical therapy for gallblad der cancer, chemotherapy for biliary tract cancers, and new histological features in CC.

KEY MESSAGE

The present review article will update the knowledge on biliary tract cancers, en hancing the quality of daily clinical practice. However, many features about these cancers remain unknown; further studies are required to establish disease-specific optimal treatment strategies.

摘要

背景

胆管癌(CC)以及胆囊癌是相对罕见且难以治疗的疾病。针对这些肿瘤的临床、病理和流行病学研究一直在进行中。2015年在意大利米兰举行的东西方肝脏肿瘤协会(EWALT)会议上报告了胆道癌的现状和/或相关议题。

总结

本文所有作者按以下顺序具体报告了胆道癌的现状和前沿研究结果:胆管癌的流行病学、肝内胆管癌的手术治疗、肝门周围胆管癌的手术治疗、胆囊癌的手术治疗、胆道癌的化疗以及胆管癌的新组织学特征。

关键信息

本综述文章将更新有关胆道癌的知识,提高日常临床实践质量。然而,这些癌症的许多特征仍不为人知;需要进一步研究以制定针对特定疾病的最佳治疗策略。

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本文引用的文献

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Biliary tract cancer registry in Japan from 2008 to 2013.2008年至2013年日本胆道癌登记情况
J Hepatobiliary Pancreat Sci. 2016 Mar;23(3):149-57. doi: 10.1002/jhbp.314. Epub 2016 Jan 26.
4
Epidemiology of cholangiocarcinoma.胆管癌的流行病学
Best Pract Res Clin Gastroenterol. 2015 Apr;29(2):221-32. doi: 10.1016/j.bpg.2015.02.003. Epub 2015 Feb 16.
6
Second-line chemotherapy in advanced biliary cancer: a systematic review.晚期胆道癌的二线化疗:系统评价。
Ann Oncol. 2014 Dec;25(12):2328-2338. doi: 10.1093/annonc/mdu162. Epub 2014 Apr 25.
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Pathogenesis, diagnosis, and management of cholangiocarcinoma.胆管癌的发病机制、诊断和治疗。
Gastroenterology. 2013 Dec;145(6):1215-29. doi: 10.1053/j.gastro.2013.10.013. Epub 2013 Oct 15.

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