Paleev N R, Odinokova V A, Smirnov V B, Gurevich M A
Sov Med. 1989(7):13-7.
The authors analyze the results of histologic and electron-microscopic studies of 58 endomyocardial biopsy specimens, obtained from patients with infectious allergic myocarditis aged 20 to 52. Morphologic examinations have been parallelled by studies of arrhythmias in these patients. The major parameters of hemodynamics at rest and dosed exercise have been examined by the radionuclide technique. Cardiac rhythm and conductivity disorders in infectious allergic myocarditis often aggravate the course of the disease, disturb the hemodynamics, and are prognostically unfavourable signs. These disorders result from changes in the myocardial membranes, and one of the mechanisms responsible for the membranous injuries are the dystrophic processes in the nerve fibres, terminals, and receptors of the myocardium.
作者分析了58例年龄在20至52岁的感染性过敏性心肌炎患者的心肌内膜活检标本的组织学和电子显微镜研究结果。对这些患者的心律失常进行了研究,与形态学检查并行。采用放射性核素技术检查了静息和定量运动时的主要血流动力学参数。感染性过敏性心肌炎中的心律失常和传导障碍常使病程加重,扰乱血流动力学,是预后不良的征象。这些障碍是由心肌膜的变化引起的,而导致膜损伤的机制之一是心肌神经纤维、终末和受体的营养不良过程。