Tran Van Dinh, James Anthony P, Lee Andy H, Jancey Jonine, Howat Peter A, Thi Phuong Mai Le
1 Department of Community Health and Network Coordination, National Institute of Hygiene and Epidemiology , Hanoi, Vietnam .
2 School of Public Health, Curtin University , Perth, Western Australia .
Metab Syndr Relat Disord. 2017 Mar;15(2):63-71. doi: 10.1089/met.2016.0113. Epub 2016 Dec 20.
Metabolic syndrome (MetS) and its subclinical diseases are now public health problems in Vietnam. This study aimed at determining the effectiveness of a physical activity and nutrition program for reducing MetS proportion and its components among adults with MetS in Hanam province, Vietnam.
A total of 417 volunteers aged 50-65 years with MetS were recruited from 10 communes. The communes were randomly allocated to an intervention group (five communes, n = 214) and a control group (five communes, n = 203). The participants in the intervention group received a nutrition and physical activity program for 6 months, whereas participants in the control group received standard diet and physical activity advice on only one occasion. Anthropometry, lipid profiles, glycemic status, and blood pressure were measured at baseline and at 6 months to evaluate program effectiveness.
In total, 175 intervention (81.8%) and 162 control (79.8%) participants completed the post-program evaluation. After controlling for the effects of clustering and confounding factors, the intervention group showed significant improvements in high-density lipoprotein cholesterol (+0.42 mM, P < 0.001), waist circumference (-1.63 cm, P < 0.001), waist-to-hip ratio (-0.024, P < 0.001), weight (-1.44 kg, P < 0.001), and body mass index (-0.59 kg/m, P < 0.001) when compared with the control group. A reduction in the MetS proportion was found in both intervention and control groups (P < 0.001), decreasing to 56.0% and 75.9%, respectively, but the post-program proportion was significantly lower among the intervention participants (P < 0.001). Furthermore, the mean number of MetS components exhibited by individuals decreased significantly in the intervention group (P < 0.001).
The community-based physical activity and nutrition program reduced MetS proportion, with significant improvements in several metabolic and anthropometric parameters for Vietnamese adults with MetS.
代谢综合征（MetS）及其亚临床疾病如今已成为越南的公共卫生问题。本研究旨在确定一项体育活动与营养计划对降低越南河南省患有MetS的成年人中MetS比例及其组成成分的有效性。
从10个公社招募了总共417名年龄在50 - 65岁之间患有MetS的志愿者。这些公社被随机分为干预组（5个公社，n = 214）和对照组（5个公社，n = 203）。干预组的参与者接受了为期6个月的营养与体育活动计划，而对照组的参与者仅一次性接受了标准饮食和体育活动建议。在基线和6个月时测量人体测量学指标、血脂谱、血糖状态和血压，以评估计划的有效性。
共有175名干预组参与者（81.8%）和162名对照组参与者（79.8%）完成了计划后的评估。在控制了聚类和混杂因素的影响后，与对照组相比，干预组在高密度脂蛋白胆固醇（+0.42 mM，P < 0.001）、腰围（-1.63 cm，P < 0.001）、腰臀比（-0.024，P < 0.001）、体重（-1.44 kg，P < 0.001）和体重指数（-0.59 kg/m²，P < 0.001）方面有显著改善。干预组和对照组的MetS比例均有所降低（P < 0.001），分别降至56.0%和75.9%，但干预组参与者计划后的比例显著更低（P < 0.001）。此外，干预组中个体表现出的MetS组成成分的平均数量显著减少（P < 0.001）。
基于社区的体育活动和营养计划降低了MetS比例，使患有MetS的越南成年人在多个代谢和人体测量学参数方面有显著改善。
