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[大鼠的氟代谢。3. 口服后在胃肠道中的分布]

[Fluoride metabolism in the rat. 3. Distribution in the gastrointestinal tract after oral application].

作者信息

Andreas M, Drauschke M, Knoch M, Göbel H, Heintzschel D

出版信息

Stomatol DDR. 1978 Aug;28(8):552-6.

PMID:280010
Abstract

With relation to the investigation of the mechanism of absorption in the gastrointestinal tract, the present third communication deals with a study of the distribution or absorption of fluorine-18 after oral application. This mode of application creates experimental conditions simulating the conditions of water fluoridation. Special attention is paid to the fluorine distribution or absorption in the following six portions: stomach, segments 1--3 of the small intestine, coecum und rectum. Furthermore, the question of its possible accumulation in the soft parts and its retention in the hard tissues were examined as compared with the results from intravenous application.

摘要

关于胃肠道吸收机制的研究,本第三次报告涉及口服后氟 - 18 的分布或吸收研究。这种应用方式创造了模拟水氟化条件的实验条件。特别关注氟在以下六个部位的分布或吸收:胃、小肠的第 1 - 3 段、盲肠和直肠。此外,与静脉注射应用的结果相比,研究了其在软组织中可能的蓄积以及在硬组织中的潴留问题。

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