Zakharova G N, Kliachkin M L, Marchenko V B, Balatskiĭ O A, Katsiia V G
Vestn Khir Im I I Grek. 1989 Apr;142(4):80-4.
The mechanisms of positive effects of plasmapheresis were studied in 52 patients with angiological pathology who were given 135 sessions of plasmapheresis. Most of the patients had obliterating atherosclerosis (28) and endarteritis (16). The clinical effect obtained in 80.7% of the patients with a severe regional ischemia was associated with the improved hemorheology (lower blood viscosity, lower fibrinogen level, higher deformability of erythrocytes), with hypocoagulation and normalization of the correlation of high and low density lipoproteins in atherosclerotic patients. These effects are of relatively long durations, the repeated courses of plasmapheresis within 6-8 months being, as a rule, successful.
对52例血管病患者进行了135次血浆置换，研究了血浆置换产生积极效果的机制。大多数患者患有闭塞性动脉粥样硬化（28例）和动脉内膜炎（16例）。80.7%患有严重局部缺血的患者获得的临床效果与血液流变学改善（血液粘度降低、纤维蛋白原水平降低、红细胞变形性增加）、低凝状态以及动脉粥样硬化患者高密度和低密度脂蛋白相关性正常化有关。这些效果持续时间相对较长，通常在6 - 8个月内重复进行血浆置换疗程是成功的。
