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[秋季呼吸道过敏中Ⅰ型超敏反应对霉菌的重要性]

[Importance of type I hypersensitivity to molds in autumnal respiratory allergies].

作者信息

Mayer K, Makesová D, Mayer J, Pospísil Z

出版信息

Vnitr Lek. 1989 Jun;35(6):551-7.

PMID:2800360
Abstract

The authors examined by means of skin tests for moulds 108 patients with the diagnosis of pollen rhinitis and/or pollen bronchial asthma. All had maximum complaints at the end of summer and in autumn and were formerly hyposensitized only by pollen allergens. Sensitization to fungi and its polyvalent character was significantly greater in subjects unsuccessfully treated by pollen hyposensitization, as moulds acted obviously as an important allergen. The authors found a low sensitivity and specificity of USOL screening preparations "Outdoor moulds" (76% and 81%) and "Indoor moulds" (74% and 93%).

摘要

作者通过霉菌皮肤试验对108例诊断为花粉性鼻炎和/或花粉性支气管哮喘的患者进行了检查。所有患者在夏末和秋季症状最为严重,且之前仅接受过花粉过敏原的脱敏治疗。在花粉脱敏治疗无效的患者中,对真菌的致敏及其多价特性明显更强,因为霉菌显然是一种重要的过敏原。作者发现USOL筛查制剂“室外霉菌”(灵敏度76%,特异性81%)和“室内霉菌”(灵敏度74%,特异性93%)的灵敏度和特异性较低。

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