Smiian I S, Fedortsiv O E
Vopr Pitan. 1989 May-Jun(3):34-7.
The intestinal microflora was investigated in 120 children aged 1 month to 2 years with different forms of hypotrophy. The majority of the children demonstrated an impairment of intestinal biocenosis manifesting by dysbacteriosis of different gravity. The relationship was discovered between the depth of the dysbiotic abnormalities and the underlying etiological factor that promoted the development of the chronic nutrition distress, hypotrophy gravity, the type of feeding, and treatment. The treatment of hypotrophy with bacterial drug inclusion made the children's intestinal microflora return to normal or appreciably improved it. The dysbiotic abnormalities in children with hypotrophy should be regarded as the result of the long-term use of antibacterial therapy (not justified in all the cases) in this patients' group, of inadequate feeding, and a considerable decrease of the body resistance.
对120名年龄在1个月至2岁、患有不同类型营养不良的儿童的肠道微生物群进行了研究。大多数儿童表现出肠道生物群落受损,表现为不同严重程度的菌群失调。发现菌群失调异常的严重程度与促使慢性营养障碍发展的潜在病因、营养不良的严重程度、喂养方式及治疗之间存在关联。使用含细菌药物治疗营养不良可使儿童肠道微生物群恢复正常或明显改善。营养不良儿童的菌群失调异常应被视为该患者群体长期使用抗菌治疗(并非所有情况都合理)、喂养不足以及身体抵抗力大幅下降的结果。