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聚醚醚酮(PEEK)与钛锁定钢板用于肱骨近端骨折固定的比较:两部分和三部分骨折的生物力学对比研究

PEEK versus titanium locking plates for proximal humerus fracture fixation: a comparative biomechanical study in two- and three-part fractures.

作者信息

Schliemann Benedikt, Seifert Robert, Theisen Christina, Gehweiler Dominic, Wähnert Dirk, Schulze Martin, Raschke Michael J, Weimann Andre

机构信息

Department of Trauma, Hand and Reconstructive Surgery, University Hospital Münster, Albert-Schweitzer-Campus 1, building W1, 48149, Münster, Germany.

AO Research Institute Davos, Clavadelerstrasse 8, 7270, Davos, Switzerland.

出版信息

Arch Orthop Trauma Surg. 2017 Jan;137(1):63-71. doi: 10.1007/s00402-016-2620-8. Epub 2016 Dec 22.

Abstract

INTRODUCTION

The high rigidity of metal implants may be a cause of failure after fixation of proximal humerus fractures. Carbon fiber-reinforced polyetheretherketone (PEEK) plates with a modulus similar to human cortical bone may help to overcome this problem. The present study assesses the biomechanical behavior of a PEEK plate compared with a titanium locking plate.

MATERIALS AND METHODS

Unstable two- and three-part fractures were simulated in 12 pairs of cadaveric humeri and were fixed with either a PEEK or a titanium locking plate using a pairwise comparison. With an optical motion capture system, the stiffness, failure load, plate bending, and the relative motion at the bone-implant interface and at the fracture site were evaluated.

RESULTS

The mean load to failure for two- and three-part fracture fixations was, respectively, 191 N (range 102-356 N) and 142 N (range 102-169 N) in the PEEK plate group compared with 286 N (range 191-395 N) and 258 N (range 155-366 N) in the titanium locking plate group. The PEEK plate showed significantly more bending in both the two- and three-part fractures (p < 0.05), an increased relative motion at the bone-implant interface and lower stiffness values (p < 0.05).

CONCLUSION

In this biomechanical study on unstable proximal humerus fractures, fixation with a PEEK plate showed lower fixation strength and increased motion at the bone-implant interface compared with a titanium locking plate.

摘要

引言

金属植入物的高刚性可能是肱骨近端骨折固定术后失败的一个原因。模量与人皮质骨相似的碳纤维增强聚醚醚酮(PEEK)钢板可能有助于克服这一问题。本研究评估了PEEK钢板与钛锁定钢板相比的生物力学行为。

材料与方法

在12对尸体肱骨上模拟不稳定的两部分和三部分骨折,并采用配对比较的方法分别用PEEK或钛锁定钢板进行固定。使用光学运动捕捉系统,评估了刚度、破坏载荷、钢板弯曲以及骨-植入物界面和骨折部位的相对运动。

结果

PEEK钢板组两部分和三部分骨折固定的平均破坏载荷分别为191N(范围102-356N)和142N(范围102-169N),而钛锁定钢板组分别为286N(范围191-395N)和258N(范围155-366N)。PEEK钢板在两部分和三部分骨折中均表现出明显更多的弯曲(p<0.05),骨-植入物界面的相对运动增加,刚度值较低(p<0.05)。

结论

在这项关于不稳定肱骨近端骨折的生物力学研究中,与钛锁定钢板相比,PEEK钢板固定显示出较低的固定强度和骨-植入物界面运动增加。

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