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六个欧洲拉丁国家15种癌症的净生存率趋势:基于SUDCAN人群的研究资料

Trends in net survival from 15 cancers in six European Latin countries: the SUDCAN population-based study material.

作者信息

Crocetti Emanuele, Bossard Nadine, Uhry Zoe, Roche Laurent, Rossi Silvia, Capocaccia Riccardo, Faivre Jean

机构信息

aRomagna Cancer Registry, Romagna Cancer Institute (IRST) IRCCS, Meldola, Forlì, Italy bNational Centre for Epidemiology, Surveillance and Health Promotion, ISS, Rome cDipartimento di Medicina Predittiva e per la Prevenzione, S.S.D. Epidemiologia Valutativa, Fondazione IRCCS Istituto Nazionale Tumori, Milano, Italy dDepartment of Biostatistics, University Hospital of Lyon eUniversity of Lyon, Lyon fUniversity of Lyon 1 gCNRS UMR 5558, Biometrics and Evolutionary Biology Laboratory (LBBE), BioMaths-Health Department, Health-Biostatistics Group, Villeurbanne hDepartment of Non-communicable Diseases and Injuries, French Institute for Public Health Surveillance (Invs), Sainte-Maurice iDigestive Cancer Registry of Burgundy, CHU de Dijon jINSERM U 866, University of Burgundy, Dijon, France.

出版信息

Eur J Cancer Prev. 2017 Jan;26 Trends in cancer net survival in six European Latin Countries: the SUDCAN study:S3-S8. doi: 10.1097/CEJ.0000000000000300.

Abstract

The aim of the SUDCAN collaborative study was to compare the net survival from 15 cancers diagnosed in 2000-2004 in six European Latin countries and provide trends in net survival and dynamics of excess mortality rates up to 5 years after diagnosis from 1992 to 2004 in France, Italy, Spain, and Switzerland, and from 2000 to 2004 in Belgium and Portugal. This paper presents a detailed description of the data analyzed and quality indicators. Incident cases from Belgium, France, Italy, Portugal, Spain, and Switzerland were retrieved from 56 general or specialized population-based cancer registries that participated in the EUROCARE-5 database. Fifteen cancer sites were analyzed. The data were checked according to the EUROCARE protocol. The percentages of excluded cases, cases based on death-certificate only, cases lost to follow-up at 5 years after diagnosis, and the proportions of microscopically verified cases were evaluated across countries and cancer sites. Data exclusions for major flaws were negligible. Cases based on death-certificate only were quite rare, except for some poor-prognosis cancers in some countries. The site-specific proportions of microscopically verified cases were generally high, but slightly lower in Italy than elsewhere. The percentage of cases lost to follow-up at 5 years after diagnosis was generally low. The net survival analyses in 2000-2004 included 873 314 tumors, whereas trend analyses included 1 426 004 tumors. The quality of the data analyzed was generally good. In fact, the analyzed data have been already checked and accepted for EUROCARE-5. However, slight differences in quality indexes, for some cancers, should be kept in mind in the interpretation of survival comparisons across countries.

摘要

SUDCAN合作研究的目的是比较2000年至2004年期间六个欧洲拉丁国家15种癌症的净生存率,并提供法国、意大利、西班牙和瑞士1992年至2004年以及比利时和葡萄牙2000年至2004年诊断后长达5年的净生存率趋势和超额死亡率动态。本文详细描述了所分析的数据和质量指标。从参与EUROCARE-5数据库的56个基于人群的一般或专科癌症登记处检索了比利时、法国、意大利、葡萄牙、西班牙和瑞士的发病病例。分析了15个癌症部位。数据根据EUROCARE方案进行了检查。评估了各国和各癌症部位排除病例的百分比、仅基于死亡证明的病例、诊断后5年失访的病例以及显微镜确诊病例的比例。因重大缺陷而排除的数据可忽略不计。仅基于死亡证明的病例非常罕见,除了一些国家的某些预后较差的癌症。显微镜确诊病例的部位特异性比例一般较高,但意大利略低于其他地方。诊断后5年失访病例的百分比一般较低。2000年至2004年的净生存分析包括873314个肿瘤,而趋势分析包括1426004个肿瘤。所分析数据的质量总体良好。事实上,所分析的数据已经过检查并被EUROCARE-5接受。然而,在解释各国之间的生存比较时,应记住某些癌症在质量指标上的细微差异。

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