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印度泪道和眼睑疾病实践模式调查(iSUPPLE)报告2:泪囊鼻腔吻合术中的丝裂霉素C和泪道支架

Indian Survey on Practice Patterns of Lacrimal and Eyelid Disorders (iSUPPLE) Report 2: Mitomycin-C and Lacrimal Stents in Dacryocystorhinostomy.

作者信息

Nair Akshay Gopinathan, Kamal Saurabh, Agarwal Aniruddha

机构信息

*Advanced Eye Hospital & Institute, Sanpada, Navi Mumbai†Lokmanya Tilak Municipal Medical College & General Hospital, Sion, Mumbai‡ProAdnexa Oculoplasty & Ocular Oncology Solutions, Faridabad, Haryana, India§Truhlsen Eye Institute, UNMC, Omaha, NE.

出版信息

J Craniofac Surg. 2016 Nov;27(8):2015-2019. doi: 10.1097/SCS.0000000000003102.

Abstract

PURPOSE

The aim of the study was to assess practice patterns on the use of intraoperative Mitomycin-C (MMC) and lacrimal stents (intubation) in dacryocystorhinostomy (DCR) for nasolacrimal duct obstruction (NLDO) among oculoplastic surgeons in India. The survey was aimed at obtaining data on the duration of stent placement and specifics regarding MMC usage namely, concentration and duration of application.

METHODS

A survey that included questions on the management of lacrimal disorders was sent in April 2015 to members of the Oculoplastic Association of India, through an email communication. The results were tabulated and analyzed.

RESULTS

External DCR is the preferred surgery of choice to treat NLDO for most oculoplastic surgeons (86%) surveyed. A majority (58%) of the respondents do not place stents during DCR routinely in their practice. Lesser experienced oculoplastic surgeons (<10 years of experience) when compared with more experienced surgeons were more likely to place stents routinely in their DCRs (59% versus 19%; P = 0.0002). Of the special situations that the respondents would consider stent placement, the most common scenarios were the presence of coexisting canalicular pathology followed by cases of previously failed DCRs. The preferred duration for stent removal was 3 months (48%). Intraoperative MMC was used routinely by only 36% of the respondents. The most common condition where they would consider intraoperative MMC was previously failed DCRs. Three minutes (25%) and 0.2 mg/mL (30%) were the preferred duration of application and concentration of MMC, respectively.

CONCLUSIONS

External DCR is the most preferred surgery for NLDO; in comparison, endoscopic DCR enjoys less popularity as the surgical procedure of choice in NLDO. Adjunctive procedures, namely intraoperative MMC and stenting of the lacrimal passages, are not routinely performed; however, previously failed DCRs are common indications when the respondents may use MMC and/or lacrimal stents. Three months is the preferred duration for stent removal. The trends regarding the concentration of MMC and the application show considerable variation, underscoring the need for evidence-based guidelines to assist oculoplastic surgeons.

摘要

目的

本研究旨在评估印度眼科整形医生在鼻泪管阻塞(NLDO)的泪囊鼻腔吻合术(DCR)中使用术中丝裂霉素-C(MMC)和泪道支架(插管)的实践模式。该调查旨在获取关于支架放置持续时间以及MMC使用细节的数据,即浓度和应用持续时间。

方法

2015年4月,通过电子邮件向印度眼科整形协会成员发送了一份包含泪道疾病管理问题的调查问卷。对结果进行了制表和分析。

结果

对于大多数接受调查的眼科整形医生(86%)而言,外部DCR是治疗NLDO的首选手术方式。大多数(58%)受访者在其日常实践中进行DCR时不常规放置支架。与经验更丰富的外科医生相比,经验较少的眼科整形医生(<10年经验)在其DCR手术中更有可能常规放置支架(59%对19%;P = 0.0002)。在受访者会考虑放置支架的特殊情况中,最常见的情况是存在并存的泪小管病变,其次是先前DCR手术失败的病例。支架取出的首选持续时间为3个月(48%)。仅36%的受访者常规使用术中MMC。他们会考虑术中使用MMC的最常见情况是先前DCR手术失败。MMC的首选应用持续时间为3分钟(25%),首选浓度为0.2mg/mL(30%)。

结论

外部DCR是治疗NLDO最首选的手术方式;相比之下,内镜下DCR作为NLDO的首选手术方式不太受欢迎。辅助手术,即术中MMC和泪道支架置入,并非常规进行;然而,先前DCR手术失败是受访者可能使用MMC和/或泪道支架的常见指征。3个月是支架取出的首选持续时间。关于MMC浓度和应用的趋势显示出相当大的差异,强调需要基于证据的指南来协助眼科整形医生。

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