Rintala E, Haapiainen R, Perhoniemi V
II. Chirurgischen Klinik, Universitäts-zentralkrankenhauses von Helsinki.
Zentralbl Chir. 1989;114(14):919-23.
Nine patients were operated on for primary adenocarcinoma of the duodenum at the Second Surgical Department of Helsinki University, between 1966 and 1985. They were three males and six females and were aged between 37 and 76 years. The average interval between primary symptoms and diagnosis was 3.2 months. Pancreatico-duodenectomy, the classical Whipple operation, was performed on seven cases, including one with liver resection. Four of the patients who had undergone radical surgery are alive (by Mai 1988), after six postoperative years have passed, on average (57 per cent). They are without metastases. Three patients died, among them one with liver resection one month from surgery and two with recurrent carcinoma after 1.2 and 1.8 years. Healing rates for primary duodenal carcinoma might be improved by more aggressive evaluation of symptoms in the upper gastro-intestinal tract and subsequent radical surgery.
1966年至1985年间，赫尔辛基大学第二外科为9例十二指肠原发性腺癌患者实施了手术。患者中男性3例，女性6例，年龄在37岁至76岁之间。首发症状出现至确诊的平均间隔时间为3.2个月。7例患者接受了经典的惠普尔胰十二指肠切除术，其中1例还进行了肝切除术。平均术后6年（截至1988年5月），接受根治性手术的患者中有4例存活（存活率为57%），且无转移。3例患者死亡，其中1例在肝切除术后1个月死亡，2例在术后1.2年和1.8年死于复发性癌。通过对上消化道症状进行更积极的评估并随后进行根治性手术，原发性十二指肠癌的治愈率可能会提高。
