[Nucleolus-like bodies and neuronal differentiation in the anterior hypothalamus of rats].

The emergence of nucleolus-like bodies was studied during differentiation of neurosecretory hypothalamic neurons. Nucleus supraopticus was studied in offspring of intact rats and in offspring of mothers injected with anti-hypothalamic antibodies stimulating hypothalamic tissue differentiation during gestation. The degree of structural and functional differentiation of neurosecretory cells correlated with the number of neurosecretory cells and of neurons with nucleolus-like bodies. The authors believe that these bodies' formation is a physiological event linked to development of specific function of neurosecretory cells. Morphologically, nucleoli and nucleolus-like bodies were different, with nucleolonemms absent in the latter.