Urban K, Fiala O
Acta Chir Orthop Traumatol Cech. 1989 Jul;56(4):343-9.
The authors discuss surgical procedures (resections and amputations) in a group of 35 patients with giant-cell bone tumours who were treated at the Orthopaedic Clinic in Hradec Králové. The diagnosis was established in cooperation by the orthopaedist, pathologist and roentgenologist. Resections were made in 24 patients, i.e. in 13 patients as primary operations, in 11 patients as secondary operations. The group comprised three tumours classified as malignant. After primary resection a relapse developed once, after secondary resection there were two relapses. Twenty-one patients, i.e. 87.5%, had no relapse. On account of two extensive relapses in soft tissues the affected extremity had to be amputated. One amputation was necessary on account of chronic osteomyelitis of the graft. The follow up period of the mentioned patients is between 3 and 26 years. The described investigation tested the possibility to extend indications of resection of giant-cell bone tumours also to conditions when the tumour perforates the affected skeleton and spreads to soft tissues in a favourable direction, i.e. muscles, without affecting important nerves and blood vessels.
作者讨论了在赫拉德茨-克拉洛韦骨科诊所接受治疗的35例骨巨细胞瘤患者的手术程序（切除术和截肢术）。诊断由骨科医生、病理学家和放射科医生共同确定。24例患者进行了切除术，其中13例为一期手术，11例为二期手术。该组包括3例被归类为恶性的肿瘤。一期切除术后复发1次，二期切除术后复发2次。21例患者（即87.5%）未复发。由于软组织广泛复发2次，不得不对患肢进行截肢。因移植骨慢性骨髓炎而进行了1次截肢。上述患者的随访期为3至26年。所描述的研究测试了将骨巨细胞瘤切除术的适应证扩大到肿瘤穿透受累骨骼并向有利方向（即肌肉）扩散到软组织而不影响重要神经和血管的情况的可能性。
