Tripathi Pratik, Rao Sheng Xiang, Zeng Meng Su
Department of Radiology, Zhongshan Hospital and Department of Medical Imaging, Shanghai Medical College, Fudan University, Shanghai Institute of Medical Imaging, Shanghai, China.
J Dig Dis. 2017 Jan;18(1):2-12. doi: 10.1111/1751-2980.12439.
Extramural venous invasion (EMVI) is associated with a poor prognosis and a poor overall survival rate in rectal cancer. It can independently predict local and distant tumor recurrences. Preoperative EMVI detection in rectal cancer is useful for determining the treatment strategy. EMVI status is beneficial for the post-treatment evaluation and analysis of rectal cancer. Magnetic resonance imaging (MRI) is a non-invasive diagnostic modality with no radiation effects. High-resolution MRI can detect EMVI with high accuracy. In addition, MRI results are equal to or even better than pathological results in the detection of medium to large EMVI in rectal cancer. MRI-detected EMVI (mrEMVI) can be used as a potential biomarker that facilitates treatment methods. This review highlights the importance of MRI before and after rectal cancer treatment. In addition, we analyze the prognostic correlation between mrEMVI and circulating tumor cells (CTC) in rectal cancer. This article may help shed light on the significance of mrEMVI.
壁外静脉侵犯（EMVI）与直肠癌的预后不良和总生存率低相关。它能够独立预测局部和远处肿瘤复发。直肠癌术前EMVI检测对于确定治疗策略很有用。EMVI状态有利于直肠癌的治疗后评估和分析。磁共振成像（MRI）是一种无辐射影响的非侵入性诊断方法。高分辨率MRI能够高精度检测EMVI。此外，在检测直肠癌中至大EMVI方面，MRI结果等同于甚至优于病理结果。MRI检测到的EMVI（mrEMVI）可作为一种有助于治疗方法选择的潜在生物标志物。本综述强调了直肠癌治疗前后MRI的重要性。此外，我们分析了mrEMVI与直肠癌循环肿瘤细胞（CTC）之间的预后相关性。本文可能有助于阐明mrEMVI的意义。
