Mugica Francisco, Nebot Àngela, Bagherpour Solmaz, Baladón Luisa, Serrano-Blanco Antonio
Computer Science Department, Universitat Politècnica de Catalunya, Barcelona, Spain.
Parc Sanitari Sant Joan de Déu, Sant Boi del Llobregat, Spain.
Technol Health Care. 2017;25(3):487-511. doi: 10.3233/THC-161289.
Major depressive disorder causes more human suffering than any other disease affecting humankind. It has a high prevalence and it is predicted that it will be among the three leading causes of disease burden by 2030. The prevalence of depression, all of its social and personal costs, and its recurrent characteristics, put heavy constraints on the ability of the public healthcare system to provide sufficient support for patients with depression. In this research, a model for continuous monitoring and tracking of depression in both short-term and long-term periods is presented. This model is based on a new qualitative reasoning approach.
This paper describes the patient assessment unit of a major depression monitoring system that has three modules: a patient progress module, based on a qualitative reasoning model; an analysis module, based on expert knowledge and a rules-based system; and the communication module. These modules base their reasoning mainly on data of the patient's mood and life events that are obtained from the patient's responses to specific questionnaires (PHQ-9, M.I.N.I. and Brugha). The patient assessment unit provides synthetic and useful information for both patients and physicians, keeps them informed of the progress of patients, and alerts them in the case of necessity.
A set of hypothetical patients has been defined based on clinically possible cases in order to perform a complete scenario evaluation. The results that have been verified by psychiatrists suggest the utility of the platform.
The proposed major depression monitoring system takes advantage of current technologies and facilitates more frequent follow-up of the progress of patients during their home stay after being diagnosed with depression by a psychiatrist.
重度抑郁症给人类带来的痛苦比其他任何影响人类的疾病都要多。其患病率很高,预计到2030年将成为疾病负担的三大主要原因之一。抑郁症的患病率、其所有的社会和个人成本以及复发特征,对公共医疗系统为抑郁症患者提供充分支持的能力造成了沉重限制。在本研究中,提出了一种用于短期和长期持续监测和跟踪抑郁症的模型。该模型基于一种新的定性推理方法。
本文描述了一个重度抑郁症监测系统的患者评估单元,它有三个模块:一个基于定性推理模型的患者进展模块;一个基于专家知识和基于规则系统的分析模块;以及通信模块。这些模块主要基于患者对特定问卷(PHQ - 9、M.I.N.I.和布鲁哈问卷)的回答所获得的患者情绪和生活事件数据进行推理。患者评估单元为患者和医生提供综合且有用的信息,让他们了解患者的进展情况,并在必要时发出警报。
为了进行完整的情景评估,基于临床可能的病例定义了一组假设患者。经精神科医生验证的结果表明了该平台的实用性。
所提出的重度抑郁症监测系统利用了当前技术,并便于在患者被精神科医生诊断为抑郁症后在家中停留期间更频繁地跟踪其进展情况。