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超重和肥胖的儿科患者发生手术部位感染的风险增加。

Overweight and Obese Pediatric Patients Have an Increased Risk of Developing a Surgical Site Infection.

作者信息

Blackwood Brian P, Gause Colin D, Harris Jamie C, Theodorou Christina M, Helenowski Irene, Lautz Timothy B, Grabowski Julia, Hunter Catherine J

机构信息

1 Department of Pediatric Surgery, Ann and Robert H. Lurie Children's Hospital of Chicago , Chicago, Illinois.

3 Department of General Surgery, Rush University Medical Center , Chicago, Illinois.

出版信息

Surg Infect (Larchmt). 2017 May-Jun;18(4):491-497. doi: 10.1089/sur.2016.179. Epub 2016 Dec 23.

Abstract

BACKGROUND

Obesity is a known risk factor in adult surgical site infections (SSIs), but its significance in pediatrics is unclear. We hypothesized that overweight and obese children have increased risk for SSI.

PATIENTS AND METHODS

A National Surgical Quality Improvement Program-Pediatric (NSQIP-P) file and single-center reviews identified surgical patients (2-18 years) who developed SSIs. Patients were classified as underweight, normal, overweight, or obese based on body mass index (BMI). Comorbidities associated with SSI were analyzed. Sub-specialties and operations were recorded.

RESULTS

National Surgical Quality Improvement Program-Pediatric review identified 66,671 patients and 1,380 SSIs. Seven hundred sixty-seven (767) were male and 613 female. Multivariable analysis revealed overweight and obese BMI to be risk factors for SSIs (odds ratio [OR] 1.23, 95% confidence interval [CI] 1.06-1.43; OR 1.43, 95% CI 1.25-1.63). Most commonly, overweight and obese cohorts had superficial incisional SSIs. Pediatric general surgery (3.6%) and cardiothoracic surgery (2.5%) had the highest rates of SSIs. Single-center review identified 115 SSIs. Of these, 29.6% were overweight or obese with few other identifiable SSI risk factors. Sub-specialties with the most SSIs were pediatric surgery and pediatric orthopedics. Appendectomy was the most common procedure associated with SSIs.

CONCLUSION

Herein we show elevated BMI to be a significant risk factor for SSIs. This information should be used in assessing and counseling pre-operative pediatric patients and families.

摘要

背景

肥胖是成人手术部位感染(SSI)的已知风险因素,但其在儿科中的意义尚不清楚。我们假设超重和肥胖儿童发生SSI的风险增加。

患者与方法

通过国家外科质量改进计划 - 儿科(NSQIP - P)文件和单中心回顾,确定发生SSI的手术患者(2至18岁)。根据体重指数(BMI)将患者分为体重过轻、正常、超重或肥胖。分析与SSI相关的合并症。记录亚专业和手术情况。

结果

国家外科质量改进计划 - 儿科回顾确定了66671例患者和1380例SSI。其中767例为男性,613例为女性。多变量分析显示超重和肥胖的BMI是SSI的风险因素(比值比[OR] 1.23,95%置信区间[CI] 1.06 - 1.43;OR 1.43,95% CI 1.25 - 1.63)。最常见的是,超重和肥胖队列发生浅表切口SSI。小儿普通外科(3.6%)和心胸外科(2.5%)的SSI发生率最高。单中心回顾确定了115例SSI。其中,29.6%为超重或肥胖,几乎没有其他可识别的SSI风险因素。SSI最多的亚专业是小儿外科和小儿骨科。阑尾切除术是与SSI相关最常见的手术。

结论

在此我们表明BMI升高是SSI的重要风险因素。该信息应用于评估和术前咨询儿科患者及其家属。

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