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巨大白色念珠菌性主动脉真菌球合并假性动脉瘤的成功手术治疗

Successful Surgical Treatment of a Huge Candida albicans Aortic Fungus Ball with Pseudoaneurysm.

作者信息

Tobinaga Satoru, Hirata Yuichirou, Saisho Hiroyuki, Wada Kumiko, Saku Kohsuke, Kikusaki Satoshi, Takaseya Tohru, Tanaka Hiroyuki

机构信息

Department of Surgery, Kurume University School of Medicine, 67 Asahi-machi, Kurume, Fukuoka, Japan. Electronic correspondence:

Department of Surgery, Kurume University School of Medicine, 67 Asahi-machi, Kurume, Fukuoka, Japan.

出版信息

J Heart Valve Dis. 2016 Jul;25(4):437-439.

PMID:28009946
Abstract

A 70-year-old woman with a history of aortic valve replacement and coronary artery bypass grafting (CABG) was transferred to the authors' hospital for further management of a three-month fever of unknown origin. Computed tomography showed a huge mass in the ascending aorta with pseudoaneurysm. Blood β-D-glucan levels were significantly high, and blood culture showed the growth of Candida albicans. The fungus ball was excised surgically, together with aortic root replacement and CABG, followed by six-month postoperative anti-fungal therapy. Early diagnosis by imaging studies followed by aggressive surgery and long-term postoperative antifungal treatment should result in a favorable outcome.

摘要

一名有主动脉瓣置换术和冠状动脉旁路移植术(CABG)病史的70岁女性因不明原因发热3个月被转至作者所在医院进行进一步治疗。计算机断层扫描显示升主动脉有一个巨大肿块并伴有假性动脉瘤。血液β-D-葡聚糖水平显著升高,血培养显示白色念珠菌生长。真菌球通过手术切除,同时进行主动脉根部置换和CABG,术后进行了6个月的抗真菌治疗。通过影像学检查进行早期诊断,随后积极手术和术后长期抗真菌治疗应能取得良好效果。

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