儿童直肠诱导麻醉。氯胺酮-咪达唑仑与氟烷用于麻醉诱导和维持的比较。

Rectal induction of anaesthesia in children. A comparison between ketamine-midazolam and halothane for induction and maintenance of anaesthesia.

作者信息

Holm-Knudsen R, Nygård E, Laub M

机构信息

Department of Anesthesia, Gentofte Hospital, University of Copenhagen, Denmark.

出版信息

Acta Anaesthesiol Scand. 1989 Aug;33(6):518-21. doi: 10.1111/j.1399-6576.1989.tb02957.x.

DOI:10.1111/j.1399-6576.1989.tb02957.x

PMID:2800995

Abstract

Thirty children were randomly allocated to one of three anaesthetic techniques. Rectal anaesthesia induction with a mixture of ketamine 10 mg.kg-1 BW and midazolam 0.2 mg.kg-1 BW and maintenance of anaesthesia with either intravenous ketamine or halothane were compared to induction and maintenance with halothane. Rectal induction was found reliable and useful. The frequency of side effects, the recovery time, and the time until the child could be discharged were similar in the groups maintained with halothane, whereas recovery was prolonged when intravenous ketamine was used for maintenance.

摘要

30名儿童被随机分配至三种麻醉技术中的一种。将氯胺酮10mg·kg⁻¹体重与咪达唑仑0.2mg·kg⁻¹体重混合进行直肠麻醉诱导，并分别使用静脉氯胺酮或氟烷维持麻醉，与使用氟烷诱导和维持麻醉进行比较。发现直肠诱导可靠且有用。在使用氟烷维持麻醉的各组中，副作用发生率、恢复时间以及患儿可出院的时间相似，而使用静脉氯胺酮维持麻醉时恢复时间延长。