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[用含抗生素的石膏植入物治疗非洲慢性骨髓炎]

[Treatment of chronic osteomyelitis in Africa with plaster implants impregnated with antibiotics].

作者信息

Bouillet R, Bouillet B, Kadima N, Gillard J

出版信息

Acta Orthop Belg. 1989;55(1):1-11.

PMID:2801055
Abstract

Nineteen African patients with osteomyelitis were treated by curettage of the lesions and packing of the bone cavities with plaster of Paris pellets containing antibiotics (Fucidin and Amoxycillin). Of 18 patients followed, 16 showed wound healing in an average of 3 to 6 weeks. Eight patients had regular roentgenographic examinations during a minimum of two months. In six of these patients, healing of the lesions and a significant osteogenic reaction were observed. The plaster pellets were resorbed in 3 to 6 weeks in all patients, and no signs of rejection were noted. In spite of insufficient follow-up due to medical conditions in Africa (Zaire), the study confirms the advantages of this simple treatment of osteomyelitis in underdeveloped countries.

摘要

19例非洲骨髓炎患者接受了病灶刮除术,并使用含抗生素(夫西地酸和阿莫西林)的巴黎石膏颗粒填充骨腔。在随访的18例患者中,16例平均在3至6周内伤口愈合。8例患者在至少两个月的时间内进行了定期X线检查。其中6例患者观察到病灶愈合及明显的成骨反应。所有患者的石膏颗粒在3至6周内被吸收,未发现排斥迹象。尽管由于非洲(扎伊尔)的医疗条件导致随访不足,但该研究证实了这种简单的骨髓炎治疗方法在欠发达国家的优势。

相似文献

1
[Treatment of chronic osteomyelitis in Africa with plaster implants impregnated with antibiotics].[用含抗生素的石膏植入物治疗非洲慢性骨髓炎]
Acta Orthop Belg. 1989;55(1):1-11.
2
Antibiotic loaded plaster of Paris pellets: an in vitro study of a possible method of local antibiotic therapy in bone infection.
Clin Orthop Relat Res. 1982 Jul(167):263-8.
3
[Treatment of bone infection by plaster of Paris pellets impregnated with antibiotics].
Pathol Biol (Paris). 1990 Jun;38(5 ( Pt 2)):543-7.
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[Plaster of Paris pellets containing antibiotics in the treatment of bone infection. New combinations of plaster with antibiotics].含抗生素的巴黎石膏颗粒治疗骨感染。石膏与抗生素的新组合
Rev Chir Orthop Reparatrice Appar Mot. 1983;69(3):239-44.
5
[Treatment of osteomyelitis. Experiences with Fucidin].[骨髓炎的治疗。使用夫西地酸的经验]
Tidsskr Nor Laegeforen. 1969 Mar 1;89(5):326-9.
6
Fucidin levels in osteomyelitis.骨髓炎中的夫西地酸水平。
J Ir Med Assoc. 1972 Oct 21;65(20):506-8.
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Tobramycin-impregnated calcium sulfate pellets for the treatment of chronic osteomyelitis in children and adolescents.妥布霉素浸渍硫酸钙微丸治疗儿童和青少年慢性骨髓炎
J Pediatr Orthop B. 2019 May;28(3):189-195. doi: 10.1097/BPB.0000000000000517.
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[Plaster of Paris: a carrier for antibiotics in the treatment of bone infections].
Acta Orthop Belg. 1993;59(3):239-48.
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[One-stage compound grafting of antibiotic-impregnated calcium sulfate and autogenous cancellous bone for the treatment of chronic calcaneal osteomyelitis].抗生素浸渍硫酸钙与自体松质骨一期复合移植治疗慢性跟骨骨髓炎
Zhongguo Gu Shang. 2014 Oct;27(10):854-7.
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Osteomyelitis of the calcaneus and talus.
J Bone Joint Surg Am. 1974 Mar;56(2):338-45.

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Antimicrob Agents Chemother. 2016 Jun 20;60(7):3897-905. doi: 10.1128/AAC.00080-16. Print 2016 Jul.
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Pharm Res. 2009 Jul;26(7):1644-56. doi: 10.1007/s11095-009-9875-5. Epub 2009 Apr 21.
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Biodegradable implants for potential use in bone infection. An in vitro study of antibiotic-loaded calcium sulphate.
可用于骨感染的生物可降解植入物。载抗生素硫酸钙的体外研究。
Int Orthop. 1995;19(3):157-61. doi: 10.1007/BF00181861.