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[用含抗生素的石膏植入物治疗非洲慢性骨髓炎]

[Treatment of chronic osteomyelitis in Africa with plaster implants impregnated with antibiotics].

作者信息

Bouillet R, Bouillet B, Kadima N, Gillard J

出版信息

Acta Orthop Belg. 1989;55(1):1-11.

PMID:2801055
Abstract

Nineteen African patients with osteomyelitis were treated by curettage of the lesions and packing of the bone cavities with plaster of Paris pellets containing antibiotics (Fucidin and Amoxycillin). Of 18 patients followed, 16 showed wound healing in an average of 3 to 6 weeks. Eight patients had regular roentgenographic examinations during a minimum of two months. In six of these patients, healing of the lesions and a significant osteogenic reaction were observed. The plaster pellets were resorbed in 3 to 6 weeks in all patients, and no signs of rejection were noted. In spite of insufficient follow-up due to medical conditions in Africa (Zaire), the study confirms the advantages of this simple treatment of osteomyelitis in underdeveloped countries.

摘要

19例非洲骨髓炎患者接受了病灶刮除术,并使用含抗生素(夫西地酸和阿莫西林)的巴黎石膏颗粒填充骨腔。在随访的18例患者中,16例平均在3至6周内伤口愈合。8例患者在至少两个月的时间内进行了定期X线检查。其中6例患者观察到病灶愈合及明显的成骨反应。所有患者的石膏颗粒在3至6周内被吸收,未发现排斥迹象。尽管由于非洲(扎伊尔)的医疗条件导致随访不足,但该研究证实了这种简单的骨髓炎治疗方法在欠发达国家的优势。

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