Double Jeopardy: The Rubber Ball Bounces Twice.

作者信息

Arbiser Jack L, Gilbert Linda C

机构信息

Department of Dermatology, Emory University School of Medicine, Atlanta Veterans Administration Medical Center, Winship Cancer Institute, Atlanta, Georgia, USA.

出版信息

J Invest Dermatol. 2017 Jan;137(1):15-17. doi: 10.1016/j.jid.2016.08.011.

DOI:10.1016/j.jid.2016.08.011

PMID:28010758

Abstract

Soblet et al. describe cis mutations in TEK/Tie-2 in blue rubber bleb nevus and sporadic vascular malformations. This suggests that the remaining normal allele is required for the phenotype. Second, it suggests therapeutic approaches to treatment signal transduction inhibition.

摘要