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全膝关节置换术前与术后的疼痛及功能变化:瑞典与澳大利亚队列的比较

Variations in pain and function before and after total knee arthroplasty: a comparison between Swedish and Australian cohorts.

作者信息

Dowsey M M, Robertsson O, Sundberg M, Lohmander L S, Choong P F M, W-Dahl A

机构信息

Department of Orthopaedics and the University of Melbourne Department of Surgery, St. Vincent's Hospital Melbourne, Australia.

Orthopaedics, Department of Clinical Sciences, Lund University, Lund, Sweden; The Swedish Knee Arthroplasty Register, Lund, Sweden.

出版信息

Osteoarthritis Cartilage. 2017 Jun;25(6):885-891. doi: 10.1016/j.joca.2016.12.018. Epub 2016 Dec 20.

Abstract

OBJECTIVE

Preoperative pain and function is viewed as an important predictor of total knee arthroplasty (TKA) outcomes. We examined whether variations in pain and function outcomes existed at 12 months between two centres in Sweden and Australia, and whether this was explained by variations in patient presentation for TKA.

METHODS

This was a retrospective analysis of prospectively collected data. Patients from one centre in Australia (St. Vincent's Hospital (SVH), N = 516) and in Sweden (Trelleborg (TBG), N = 899) who underwent primary TKA between 2012 and 2013. The Western Ontario and McMaster Universities Arthritis Index (WOMAC) was analysed pre- and 12 months' post TKA from which non-response to surgery was determined using the OMERACT-OARSI criteria. Multiple linear regression analysis was used to examine the relationship between change in pain and function and surgery centre, adjusting for preoperative patient characteristics and surgical technique.

RESULTS

Despite worse preoperative outcomes in all subscales of the WOMAC for the SVH cohort, there were no clinically meaningful differences in 12-month WOMAC subscales nor change in WOMAC subscales between SVH and TBG. Almost identical proportions of patients were considered OMERACT-OARSI responders, 85.7% (SVH) and 85.9% (TBG), however for the SVH cohort 25 (4.9%) were moderate and 417 (80.8%) were high responders, compared to the TBG cohort of which 225 (25%) were moderate and 547 (60.9%) were high responders.

CONCLUSION

Despite differences in preoperative presentation between 2 countries, improvements in pain and function and the proportion of individual who responded to TKA surgery at 1 year were similar. Factors related to poor response to TKA surgery require further elucidation.

摘要

目的

术前疼痛和功能被视为全膝关节置换术(TKA)预后的重要预测指标。我们研究了瑞典和澳大利亚两个中心在术后12个月时疼痛和功能预后是否存在差异,以及这是否可以通过TKA患者表现的差异来解释。

方法

这是一项对前瞻性收集数据的回顾性分析。来自澳大利亚一个中心(圣文森特医院(SVH),N = 516)和瑞典一个中心(特雷勒堡(TBG),N = 899)的患者在2012年至2013年间接受了初次TKA。对TKA术前和术后12个月的西安大略和麦克马斯特大学关节炎指数(WOMAC)进行分析,并根据OMERACT - OARSI标准确定手术无反应情况。采用多元线性回归分析来研究疼痛和功能变化与手术中心之间的关系,并对术前患者特征和手术技术进行调整。

结果

尽管SVH队列的WOMAC所有子量表术前预后较差,但SVH和TBG在术后12个月的WOMAC子量表上没有临床意义上的差异,WOMAC子量表的变化也无差异。几乎相同比例的患者被视为OMERACT - OARSI反应者,分别为85.7%(SVH)和85.9%(TBG),然而SVH队列中有25例(4.9%)为中度反应者,417例(80.8%)为高度反应者,相比之下,TBG队列中有225例(25%)为中度反应者,547例(60.9%)为高度反应者。

结论

尽管两个国家术前表现存在差异,但疼痛和功能的改善以及1年时对TKA手术有反应的个体比例相似。与TKA手术反应不佳相关因素需要进一步阐明。

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