Fanari Zaher, Elliott Daniel, Russo Carla A, Kolm Paul, Weintraub William S
Section of Cardiology, Christiana Care Health System, Newark, DE; Division of Cardiology, University of Kansas School of Medicine.
Department of Medicine, Christiana Care Health System, Newark, DE; Value Institute, Christiana Care Health System, Newark, DE.
Cardiovasc Revasc Med. 2017 Mar;18(2):100-104. doi: 10.1016/j.carrev.2016.12.003. Epub 2016 Dec 15.
To investigate whether a prediction model based on data available early in percutaneous coronary intervention (PCI) admission can predict the risk of readmission.
Reducing readmissions following hospitalization is a national priority. Identifying patients at high risk for readmission after PCI early in a hospitalization would enable hospitals to enhance discharge planning.
We developed 3 different models to predict 30-day inpatient readmission to our institution for patients who underwent PCI between January 2010 and April 2013. These models used data available: 1) at admission, 2) at discharge 3) from CathPCI Registry data. We used logistic regression and assessed the discrimination of each model using the c-index. The models were validated with testing on a different patient cohort who underwent PCI between May 2013 and September 2015.
Our cohort included 6717 PCI patients; 3739 in the derivation cohort and 2978 in the validation cohort. The discriminative ability of the admission model was good (C-index of 0.727). The c-indices for the discharge and cath PCI models were slightly better. (C-index of 0.751 and 0.752 respectively). Internal validation of the models showed a reasonable discriminative admission model with slight improvement with adding discharge and registry data (C-index of 0.720, 0.739 and 0.741 respectively). Similarly validation of the models on the validation cohort showed similar results (C-index of 0.703, 0.725 and 0.719 respectively).
Simple models based on available demographic and clinical data may be sufficient to identify patients at highest risk of readmission following PCI early in their hospitalization.
探讨基于经皮冠状动脉介入治疗(PCI)入院早期可得数据的预测模型能否预测再入院风险。
降低住院后的再入院率是一项国家重点工作。在住院早期识别PCI术后再入院高风险患者,将使医院能够加强出院计划。
我们开发了3种不同模型,以预测2010年1月至2013年4月期间接受PCI治疗的患者30天内再次入住我院的情况。这些模型使用了可得数据:1)入院时,2)出院时,3)来自心脏PCI注册数据。我们使用逻辑回归,并使用c指数评估每个模型的辨别力。这些模型在2013年5月至2015年9月期间接受PCI治疗的不同患者队列中进行测试验证。
我们的队列包括6717例PCI患者;推导队列中有3739例,验证队列中有2978例。入院模型的辨别能力良好(c指数为0.727)。出院模型和心脏PCI模型的c指数略高(分别为0.751和0.752)。模型的内部验证显示,入院模型辨别力合理,加入出院和注册数据后略有改善(c指数分别为0.720、0.739和0.741)。同样,在验证队列中对模型进行验证也显示了类似结果(c指数分别为0.703、0.725和0.719)。
基于可得的人口统计学和临床数据的简单模型可能足以识别住院早期PCI术后再入院风险最高的患者。