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[Studies on synthesis of baogongteng A--a new myotic agent].

作者信息

Xiang Z, Zhou J E, Chen Z N, Wang L P, Wang H N, Yao T R, Xie J X, Xu G Y, Yi D N

出版信息

Yao Xue Xue Bao. 1989;24(2):105-9.

PMID:2801130
Abstract

Baogongteng A, isolated from Erycibe obtusifolia Benth., is a new tropane alkaloid used for treating glaucoma. Using synthetic 6 beta-acetoxy-tropinone as starting material, racemic Baogongteng A(8) was synthesized. Synthetic Baogongteng A also shows myotic activities in rabbits, but the potency is half of that of the natural product.

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