Guo Yufang, Lam Louisa, Luo Yuanhui, Plummer Virginia, Cross Wendy, Li Hui, Yin Yizhen, Zhang Jingping
Nursing Psychology Research Center of Xiangya Nursing School, Central South University, Changsha, 410013, Hunan, China.
School of Nursing and Midwifery, Faculty of Medicine, Nursing and Health Sciences, Monash University, 3800, Melbourne Victoria, Australia.
Psychoneuroendocrinology. 2017 Mar;77:47-50. doi: 10.1016/j.psyneuen.2016.11.020. Epub 2016 Nov 24.
Across the world, hospital nurses experience a high level of burnout. Exploring biochemical markers of burnout could help to understand physiological changes and may provide useful evidence for preventing burnout symptoms. The current study included 94 female nurses from one Chinese third-level hospital. The Maslach Burnout Inventory-General Survey (MBI-GS) was used to investigate burnout symptoms: emotional exhaustion, cynicism, reduced professional efficacy, as well as the burnout average. The HPT axis was tested by checking blood levels of thyroid-stimulating hormone (TSH), thyroxin (T) and triiodothyronine (T). Nonparametric tests showed that no significant difference in biochemical markers was found between the burnout and non-burnout groups. Spearman correlation analysis found that biochemical markers had no significant association with burnout symptoms, except weakly negative associations between reduced professional efficacy and blood pressure and heart rate. These findings show a rather poor correlation of the HPT axis on burnout symptoms. Expanding the biochemical index of the HPT axis, comparing well-defined samples and using longitudinal studies are recommended for further studies.
在全球范围内，医院护士面临着高度的职业倦怠。探索职业倦怠的生化标志物有助于了解生理变化，并可能为预防职业倦怠症状提供有用的证据。本研究纳入了来自一家中国三级医院的94名女性护士。采用马氏职业倦怠量表通用版（MBI-GS）调查职业倦怠症状：情感耗竭、玩世不恭、职业效能降低以及职业倦怠平均分。通过检测促甲状腺激素（TSH）、甲状腺素（T）和三碘甲状腺原氨酸（T）的血液水平来检测下丘脑-垂体-甲状腺（HPT）轴。非参数检验表明，职业倦怠组和非职业倦怠组之间在生化标志物上未发现显著差异。Spearman相关分析发现，生化标志物与职业倦怠症状无显著关联，但职业效能降低与血压和心率之间存在微弱的负相关。这些发现表明HPT轴与职业倦怠症状的相关性相当低。建议进一步研究扩大HPT轴的生化指标、比较明确界定的样本并采用纵向研究。
