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一例由先前未确诊的小叶性乳腺癌导致小肠梗阻的病例报告:澳大利亚文献首例。

A case report of small bowel obstruction from previously undiagnosed lobular breast carcinoma: First in Australian literature.

作者信息

Cristaudo Adam Thomas, Zhu Katherine Jing

机构信息

Department of General Surgery, Redcliffe Hospital, QLD, 4020, Australia; Westmead Research Centre for Evaluation of Surgical Outcomes, Department of Surgery, University of Sydney, Westmead Hospital, Westmead, NSW, 2145, Australia.

Department of General Surgery, Redcliffe Hospital, QLD, 4020, Australia.

出版信息

Int J Surg Case Rep. 2017;30:152-154. doi: 10.1016/j.ijscr.2016.11.056. Epub 2016 Nov 30.

Abstract

INTRODUCTION

This case report is the first in the Australian literature of a patient, without prior diagnosis, presenting with a bowel obstruction secondary to lobular breast cancer. This highlights a relatively rare cause of bowel obstruction, but also the importance of breast self-examination as a compliment to the current BreastScreen Australia program.

PRESENTATION OF CASE

A 67-year-old female presented to the Emergency Department with a 48-h history of sharp, constant epigastric pain, vomiting and constipation. The patient proceeded to emergency laparotomy for presumed large bowel obstruction, which revealed a stricture in the distal terminal ileum causing a distal small bowel obstruction. A right hemicolectomy was performed. Histopathology revealed the terminal ileum stricture to be metastatic lobular breast carcinoma. Clinical examination of the patient's right breast revealed a lesion suggestive of the primary malignancy despite a normal ultrasound and mammogram in 2014. After failing to progress, a CT scan was performed which revealed progressive small and large bowel distension. A repeat laparotomy was performed revealing dilated large bowel without obstructing pathology and an intact anastomosis. A loop ileostomy was performed. Following a further febrile episode, the patient decided to withdraw care and the patient passed away three weeks into her admission from suspected intra-abdominal sepsis.

DISCUSSION

Breast cancer is becoming the third most common cancer amongst Australian women with a significant burden of disease and mortality.

CONCLUSION

Despite the rare presentation, this case reminds the medical community and general population of the importance of breast self-examination and the BreastScreen Australia program.

摘要

引言

本病例报告是澳大利亚文献中首例未经过先前诊断,因小叶型乳腺癌继发肠梗阻就诊的患者。这凸显了肠梗阻一种相对罕见的病因,同时也强调了乳房自我检查作为澳大利亚现行乳房筛查计划补充手段的重要性。

病例介绍

一名67岁女性因上腹部剧痛、持续48小时的呕吐和便秘前往急诊科就诊。患者因疑似大肠梗阻接受了急诊剖腹手术,术中发现回肠末端远端狭窄导致小肠远端梗阻。遂进行了右半结肠切除术。组织病理学检查显示回肠末端狭窄为转移性小叶型乳腺癌。尽管患者右乳在2014年超声和乳房X线检查均正常,但临床检查发现一个病变提示原发性恶性肿瘤。病情无进展后,进行了CT扫描,显示大小肠逐渐扩张。再次进行剖腹手术,发现大肠扩张但无梗阻性病变,吻合口完好。遂进行了回肠造口术。在又一次发热发作后,患者决定放弃治疗,入院三周后因疑似腹腔内感染去世。

讨论

乳腺癌正成为澳大利亚女性中第三大最常见的癌症,疾病负担和死亡率都很高。

结论

尽管该病例表现罕见,但它提醒了医学界和普通民众乳房自我检查以及澳大利亚乳房筛查计划的重要性。

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