Firat University School of Medicine Department of Psychiatry, Elazig, Turkey.
Firat University School of Medicine Department of Psychiatry, Elazig, Turkey.
Psychiatry Res Neuroimaging. 2017 Feb 28;260:49-52. doi: 10.1016/j.pscychresns.2016.12.004. Epub 2016 Dec 6.
In pubertal and postpubertal patients with post-traumatic stress disorder (PTSD), significantly greater pituitary gland volumes have been reported. Moving from this point, in the present study, we aimed to investigate pituitary gland volumes in patients with PTSD and hypothesized that volumes of the gland would be structurally changed. Volumetric magnetic resonance imaging of the pituitary gland was performed among sixteen patients with PTSD and fifteen healthy control subjects. We found that the mean volume of the pituitary gland was statistically significant and smaller than that of healthy subjects (0.69±0.08cm for patient group and 0.83±0.21 for control subjects). Consequently, in the present study, we found that patients with PTSD had smaller pituitary gland volumes than those of healthy controls like other anxiety disorders. It is important to provide support for this finding in future longitudinal investigations.
在患有创伤后应激障碍（PTSD）的青春期和青春期后的患者中，已报道垂体体积明显增大。从这一点出发，在本研究中，我们旨在研究 PTSD 患者的垂体体积，并假设腺体的体积将发生结构性变化。对 16 名 PTSD 患者和 15 名健康对照者进行了垂体磁共振成像体积测量。我们发现，垂体的平均体积具有统计学意义且小于健康对照组（患者组为 0.69±0.08cm，对照组为 0.83±0.21cm）。因此，在本研究中，我们发现与其他焦虑症一样，患有 PTSD 的患者的垂体体积比健康对照组小。在未来的纵向研究中，为这一发现提供支持很重要。
