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轻度创伤性脑损伤后应激障碍患者应激障碍的变化及影响因素。

Changes and Influencing Factors of Stress Disorder in Patients with Mild Traumatic Brain Injury Stress Disorder.

机构信息

Nursing School, Qiqihar Medical University, Qiqihar, 161006 Heilongjiang, China.

Department of Nursing, The Fourth Affiliated Hospital of Qiqihar Medical University, Qiqihar, 161000 Heilongjiang, China.

出版信息

Biomed Res Int. 2022 Sep 26;2022:9082946. doi: 10.1155/2022/9082946. eCollection 2022.

DOI:10.1155/2022/9082946
PMID:36199756
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9529484/
Abstract

Traumatic brain injury (TBI) is a brain injury caused by motor vehicle accidents, falls from heights, sports, and combat. Posttraumatic stress disorder (PTSD) is a complex mental disorder caused by physical and psychological trauma, which manifests itself with symptoms such as anxiety, depression, and cognitive dysfunction. How its symptoms arise and what factors influence it are not fully understood nor can it be predicted. In order to better understand the changes after stress disorder in TBI patients and the influencing factors of PTSD, this paper analyzed the changes and influencing factors of stress disorder in patients with mild traumatic brain injury stress disorder. In this paper, the Wechsler Memory Scale and functional magnetic resonance imaging were first used to study the memory impairment and functional changes of corresponding brain regions in patients with TBI stress disorder, and then, the Pittsburgh Sleep Quality Index Scale and the pain Visual Analogue Scale were used to study the influencing factors of PTSD. The results of the study showed that PTSD patients reduced and enhanced regional brain functional activity and impaired memory function in the resting state. Male gender, age under 45 years, no hemiplegia, and good sleep quality were protective factors for PTSD in TBI patients. The need for drug-assisted sleep, severe headache, and moderate headache was the risk factor for PTSD in TBI patients.

摘要

创伤性脑损伤(TBI)是由机动车事故、高处坠落、运动和战斗引起的脑损伤。创伤后应激障碍(PTSD)是一种由身体和心理创伤引起的复杂精神障碍,表现为焦虑、抑郁和认知功能障碍等症状。其症状的出现及其影响因素尚不完全清楚,也无法预测。为了更好地了解 TBI 患者应激障碍后的变化和 PTSD 的影响因素,本文分析了轻度创伤性脑损伤应激障碍患者应激障碍的变化和影响因素。本文首先采用韦氏记忆量表和功能磁共振成像研究 TBI 应激障碍患者的记忆障碍和相应脑区的功能变化,然后采用匹兹堡睡眠质量指数量表和疼痛视觉模拟量表研究 PTSD 的影响因素。研究结果表明,PTSD 患者在静息状态下的局部脑功能活动减少和增强,记忆功能受损。男性、年龄小于 45 岁、无偏瘫、睡眠质量好是 TBI 患者 PTSD 的保护因素。需要药物辅助睡眠、严重头痛和中度头痛是 TBI 患者 PTSD 的风险因素。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c70/9529484/6e0ea2b82777/BMRI2022-9082946.010.jpg
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