Kharroubi Akram, Saba Elias, Ghannam Ibrahim, Darwish Hisham
Faculty of Health Professions, Al-Quds University, Jerusalem, Palestine.
Palestinian Osteoporosis Prevention Society [POPS], Bethlehem, Palestine.
Arch Osteoporos. 2017 Dec;12(1):6. doi: 10.1007/s11657-016-0298-8. Epub 2016 Dec 24.
The need for simple self-assessment tools is necessary to predict women at high risk for developing osteoporosis. In this study, tools like the IOF One Minute Test, Fracture Risk Assessment Tool (FRAX), and Simple Calculated Osteoporosis Risk Estimation (SCORE) were found to be valid for Palestinian women. The threshold for predicting women at risk for each tool was estimated.
The purpose of this study is to evaluate the validity of the updated IOF (International Osteoporosis Foundation) One Minute Osteoporosis Risk Assessment Test, FRAX, SCORE as well as age alone to detect the risk of developing osteoporosis in postmenopausal Palestinian women.
Three hundred eighty-two women 45 years and older were recruited including 131 women with osteoporosis and 251 controls following bone mineral density (BMD) measurement, 287 completed questionnaires of the different risk assessment tools. Receiver operating characteristic (ROC) curves were evaluated for each tool using bone BMD as the gold standard for osteoporosis.
The area under the ROC curve (AUC) was the highest for FRAX calculated with BMD for predicting hip fractures (0.897) followed by FRAX for major fractures (0.826) with cut-off values ˃1.5 and ˃7.8%, respectively. The IOF One Minute Test AUC (0.629) was the lowest compared to other tested tools but with sufficient accuracy for predicting the risk of developing osteoporosis with a cut-off value ˃4 total yes questions out of 18. SCORE test and age alone were also as good predictors of risk for developing osteoporosis. According to the ROC curve for age, women ≥64 years had a higher risk of developing osteoporosis. Higher percentage of women with low BMD (T-score ≤-1.5) or osteoporosis (T-score ≤-2.5) was found among women who were not exposed to the sun, who had menopause before the age of 45 years, or had lower body mass index (BMI) compared to controls. Women who often fall had lower BMI and approximately 27% of the recruited postmenopausal Palestinian women had accidents that caused fractures.
Simple self-assessment tools like FRAX without BMD, SCORE, and the IOF One Minute Tests were valid for predicting Palestinian postmenopausal women at high risk of developing osteoporosis.
需要简单的自我评估工具来预测有患骨质疏松症高风险的女性。在本研究中，国际骨质疏松症基金会（IOF）一分钟测试、骨折风险评估工具（FRAX）和简易计算骨质疏松症风险评估（SCORE）等工具被发现对巴勒斯坦女性有效。估算了每种工具预测有风险女性的阈值。
本研究的目的是评估更新后的国际骨质疏松症基金会（IOF）一分钟骨质疏松症风险评估测试、FRAX、SCORE以及仅年龄因素检测绝经后巴勒斯坦女性患骨质疏松症风险的有效性。
招募了382名45岁及以上的女性，包括131名骨质疏松症女性和251名对照，进行骨密度（BMD）测量，287人完成了不同风险评估工具的问卷调查。以骨密度作为骨质疏松症的金标准，对每种工具评估受试者工作特征（ROC）曲线。
用骨密度计算的FRAX预测髋部骨折的ROC曲线下面积（AUC）最高（0.897），其次是预测主要骨折的FRAX（0.826），截断值分别为>1.5%和>7.8%。与其他测试工具相比，IOF一分钟测试的AUC（0.629）最低，但预测患骨质疏松症风险的准确性足够，截断值为18个问题中肯定回答总数>4个。SCORE测试和仅年龄因素也是患骨质疏松症风险的良好预测指标。根据年龄的ROC曲线，≥64岁的女性患骨质疏松症的风险更高。与对照组相比，未暴露于阳光下、45岁前绝经或体重指数（BMI）较低的女性中，骨密度低（T值≤-1.5）或患骨质疏松症（T值≤-2.5）的女性比例更高。经常跌倒的女性BMI较低，约27%的招募的绝经后巴勒斯坦女性发生过导致骨折的意外事故。
像不依赖骨密度的FRAX、SCORE和IOF一分钟测试这样的简单自我评估工具对预测有患骨质疏松症高风险的绝经后巴勒斯坦女性是有效的。
