Weight carrying versus handgrip exercise testing in men with coronary artery disease.

The clinical merits of handgrip and weight carrying tests were compared in 30 patients with documented coronary artery disease. The static loads in the 2 tests were matched by percentage of maximal static effort and corresponded to 25 and 45% of maximal voluntary handgrip contraction and 25 and 45% of maximal 1-hand lift capacity. Each static load in both tests was continued for less than or equal to 3 minutes. At the 25% maximal effort stage, 93 and 90% of patients were able to complete 3 minutes of handgrip and weight carrying, respectively. Only 13 and 10% were able to complete 3 minutes at the 45% maximal effort stage with handgrip and weight carrying, respectively. Arm fatigue and an increase in diastolic blood pressure greater than 120 mm Hg were the predominant endpoints. Weight carrying resulted in significantly higher (p less than 0.05) heart rate, systolic blood pressure, pressure-rate product, ventilation and oxygen consumption compared to handgrip. Diastolic blood pressure responses did not differ between the tests. None of the patients demonstrated ischemic responses to either handgrip or weight carrying and the incidence of arrhythmias was rare. The diastolic blood pressure response to static effort is equally evaluated by handgrip and weight carrying tests. However, the greater myocardial oxygen demand, reflected by the pressure-rate product, in addition to the greater total body oxygen consumption, imposed by weight carrying, enhances the clinical application of the weight carrying test.