Malone C Helen, Goodwin Brandon, Wagner Richard F, Resto Vicente, Kelly Brent
Department of Dermatology, The University of Texas Medical Branch, Galveston, TX 77555, USA.
Department of Otolaryngology, The University of Texas Medical Branch, Galveston, TX 77555, USA.
Case Rep Dermatol Med. 2016;2016:6074182. doi: 10.1155/2016/6074182. Epub 2016 Nov 27.
Dermatofibrosarcoma protuberans (DFSP) is an unusual spindle cell tumor with a high rate of local recurrence with traditional excision. Fortunately, Mohs micrographic surgery yields excellent cure rates for this neoplasm due to contiguous tumor spread and meticulous tumor mapping and margin analysis. We present the unique case of a patient treated with a modified Mohs technique with an analysis of the final margin with permanent sections, who developed a spindle cell neoplasm in the margins of her second stage excision consistent with nodular fasciitis. Distinguishing residual DFSP from a benign reactive process was an essential and challenging component of this patient's management.
隆突性皮肤纤维肉瘤（DFSP）是一种不常见的梭形细胞肿瘤，采用传统切除术时局部复发率很高。幸运的是，由于肿瘤呈连续性扩散以及细致的肿瘤定位和切缘分析，莫氏显微外科手术对这种肿瘤的治愈率很高。我们报告了一例采用改良莫氏技术治疗的独特病例，并对最终切缘进行了永久切片分析，该患者在二期切除切缘处发生了一种与结节性筋膜炎一致的梭形细胞肿瘤。将残留的DFSP与良性反应性病变区分开来是该患者治疗过程中的一个关键且具有挑战性的环节。
