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根据中国南方参考数据集估算的中国北方人群牙齿年龄与实际年龄密切相关。

Northern Chinese dental ages estimated from southern Chinese reference datasets closely correlate with chronological age.

作者信息

Wong Hai Ming, Wen Yi Feng, Jayaraman Jayakumar, Li Jing, Sun Ling, King Nigel Martyn, Roberts Graham J

机构信息

Paediatric Dentistry, Faculty of Dentistry, The University of Hong Kong, Prince Philip Dental Hospital, 34 Hospital Road, Sai Ying Pun, Hong Kong.

School of Dentistry, International Medical University, Kuala Lumpur, Malaysia.

出版信息

Heliyon. 2016 Dec 16;2(12):e00216. doi: 10.1016/j.heliyon.2016.e00216. eCollection 2016 Dec.

Abstract

While northern and southern Chinese are genetically correlated, there exists notable environmental differences in their living conditions. This study aimed to evaluate validity of the southern Chinese reference dataset for dental age estimation applied to northern Chinese. Dental panoramic tomographs of 437 northern Chinese aged 3 to 21 years were analysed. All the left maxillary and mandibular permanent teeth plus the 2 third molars on the right side were scored based on Demirjian's classification of tooth development stages. Mean and standard error of dental age were obtained for each tooth development stage, followed by random effect meta-analysis for mean dental age estimation. Validity of the method was examined through measures of agreement (95% limits of agreement, standard error of measurement, and Lin's concordance correlation coefficient) and measure of reliability (Intraclass correlation coefficient). On average, the estimated dental age overestimated chronological age by only around 1 month in both females and males. The Intraclass correlation coefficient values were 0.99 for both sexes, suggesting excellent reliability of the method. Reference dataset for dental age estimation developed on the basis of southern Chinese was applicable for use among the northern Chinese.

摘要

虽然中国北方人和南方人在基因上存在关联,但他们的生活环境存在显著差异。本研究旨在评估应用于中国北方人的南方人牙齿年龄估计参考数据集的有效性。分析了437名年龄在3至21岁之间的中国北方人的口腔全景断层扫描图像。根据德米尔坚牙齿发育阶段分类法,对所有左侧上颌和下颌恒牙以及右侧的2颗第三磨牙进行评分。获得每个牙齿发育阶段的牙齿年龄均值和标准误差,随后对牙齿年龄估计均值进行随机效应荟萃分析。通过一致性测量指标(95%一致性界限、测量标准误差和林氏一致性相关系数)和可靠性测量指标(组内相关系数)来检验该方法的有效性。平均而言,在女性和男性中,估计的牙齿年龄仅比实际年龄高估约1个月。两性的组内相关系数值均为0.99,表明该方法具有出色的可靠性。基于中国南方人开发的牙齿年龄估计参考数据集适用于中国北方人。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0aa8/5176030/98ae753ed236/gr1.jpg

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