Popova M, Karag'ozov A, Nikolova D, Khristova D, Milev A
Akush Ginekol (Sofiia). 1989;28(3):60-3.
The quick increase of morbidity, caused by the endometrial carcinoma in our country during recent 15 years from 5,2 to 16,5 per 100,000 raises acutely the question about effective primary and secondary prophylaxis. Having in mind the role of hyperestrogenemia in the etiology of endometrial carcinoma and the fact that the results from its treatment are determined basically by the degree of distribution of the tumor, the authors think that it is necessary fight for rational feeding, timely treatment of the disease with hyperestrogenemia and prophylactic therapy with gestagens. Cytologic examination of aspirate, obtained from the uterine cavity, is proposed as screening method for women of the risk groups. A scheme of management of women with pathological R3-5 group is proposed.
在我国，子宫内膜癌的发病率在最近15年中迅速上升，从每10万人5.2例增至16.5例，这使得有效一级和二级预防的问题亟待解决。考虑到高雌激素血症在子宫内膜癌病因学中的作用，以及其治疗效果基本取决于肿瘤扩散程度这一事实，作者认为有必要倡导合理饮食，及时治疗高雌激素血症相关疾病，并采用孕激素进行预防性治疗。建议对高危组女性采用宫腔吸出物细胞学检查作为筛查方法。提出了对病理R3 - 5组女性的处理方案。
