Longacre T A, Foucar K, Koster F, Burgdorf W
Department of Pathology, University of New Mexico, Albuquerque.
Am J Dermatopathol. 1989 Oct;11(5):451-6. doi: 10.1097/00000372-198910000-00007.
A variety of neoplastic disorders have been described in patients with AIDS. Kaposi's sarcoma is the most common neoplasm and is recognized as one of the diagnostic criteria for AIDS. Unusual mucocutaneous carcinomas have also been reported in these patients, as have a variety of lymphoid neoplasms, including Hodgkin's and non-Hodgkin's lymphomas (NHLs). The NHLs that occur in AIDS patients are usually of B-cell or non-B, non-T-cell phenotype. In contrast, T-cell lymphomas have only rarely been reported in this patient population. We present the clinical, morphologic, and immunologic features of an atypical, cutaneous lymphoproliferative disorder resembling mycosis fungoides that developed in a 28-year-old homosexual man with AIDS and disseminated mucocutaneous Kaposi's sarcoma.
艾滋病患者中已发现多种肿瘤性疾病。卡波西肉瘤是最常见的肿瘤，被视为艾滋病的诊断标准之一。这些患者中也报告了不常见的黏膜皮肤癌，以及多种淋巴样肿瘤，包括霍奇金淋巴瘤和非霍奇金淋巴瘤（NHL）。艾滋病患者中发生的NHL通常为B细胞或非B、非T细胞表型。相比之下，T细胞淋巴瘤在该患者群体中仅有罕见报道。我们报告了一名28岁患有艾滋病且有播散性黏膜皮肤卡波西肉瘤的同性恋男性所患的一种类似蕈样肉芽肿的非典型皮肤淋巴增殖性疾病的临床、形态学和免疫学特征。
