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孤立性甲状腺结节:审计显示改善护理需要细胞学诊断。

Solitary thyroid nodule: audit shows improved care requires cytological diagnosis.

作者信息

Wetzig N R, Giddings A E

机构信息

Royal Surrey County Hospital, Guildford.

出版信息

Ann R Coll Surg Engl. 1989 Sep;71(5):316-9.

Abstract

An audit was conducted of all patients undergoing thyroid surgery in a district general hospital over the 8-year period during which fine needle aspiration cytology (FNAC) was introduced. Of the 252 patients, 32 (14%) were toxic and 92 (36%) had large multinodular goitres, but 118 (46%) had a solitary thyroid nodule removed to exclude neoplasm. However, only 12.7% of such resected nodules were found to be carcinomas. Where FNAC was used, the accuracy for preoperative diagnosis was 82.6% and the sensitivity for prediction of carcinoma was 87.5%. Cytology correctly predicted 81% of the colloid nodules and these may have been managed without surgery if the patient was agreeable. It is suggested that one-half of the patients with solitary thyroid nodules could have been spared operation. Analysis of the operative procedure shows that one-fifth of the neoplasms may have been more accurately dealt with had FNAC been used, and four patients could have avoided the trauma and risks of a second operation. The study suggests that FNAC and increased specialisation will improve the quality of thyroid surgery in a district general hospital.

摘要

对一家地区综合医院在引入细针穿刺细胞学检查(FNAC)后的8年期间内所有接受甲状腺手术的患者进行了一项审计。在252例患者中,32例(14%)为毒性甲状腺肿,92例(36%)有巨大结节性甲状腺肿,但118例(46%)因排除肿瘤而切除了单个甲状腺结节。然而,此类切除的结节中仅12.7%被发现为癌。在使用FNAC的情况下,术前诊断的准确率为82.6%,预测癌的敏感性为87.5%。细胞学检查正确预测了81%的胶样结节,如果患者同意,这些结节可能无需手术治疗。建议一半的单个甲状腺结节患者可以避免手术。对手术过程的分析表明,如果使用FNAC,五分之一的肿瘤可能会得到更准确的处理,并且有4名患者可以避免二次手术的创伤和风险。该研究表明,FNAC和增加专业化程度将提高地区综合医院甲状腺手术的质量。

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