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鼻阻塞和鼻窦炎治疗中的证据及证据空白

Evidence and evidence gaps in therapies of nasal obstruction and rhinosinusitis.

作者信息

Rotter Nicole

机构信息

Department of Otolaryngology, Head and Neck Surgery, Ulm University Medical Centre, Ulm, Germany.

出版信息

GMS Curr Top Otorhinolaryngol Head Neck Surg. 2016 Dec 15;15:Doc06. doi: 10.3205/cto000133. eCollection 2016.

DOI:10.3205/cto000133
PMID:28025606
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5169079/
Abstract

Therapeutic decisions in otorhinolaryngology are based on clinical experience, surgical skills, and scientific evidence. Recently, evidence-based therapies have gained increased attention and importance due to their potential to improve the individual patient's treatment and their potential at the same time to reduce treatment costs. In clinical practice, it is almost impossible to stay ahead of the increasing mass of literature and on the other hand critically assess the presented data. A solid scientific and statistical knowledge as well as a significant amount of spare time are required to detect systematic bias and other errors in study designs, also with respect to assessing whether or not a study should be part of an individual therapeutic decision. Meta-analyses, reviews, and clinical guidelines are, therefore, of increasing importance for evidence-based therapy in clinical practice. This review is an update of the availability of external evidence for the treatment of nasal obstruction and rhinosinusitis. It becomes evident that both groups of diseases differ significantly in the availability of external evidence. Furthermore, it becomes obvious that surgical treatment options are normally based on evidence of significantly lower quality than medical treatment options.

摘要

耳鼻咽喉科的治疗决策基于临床经验、手术技巧和科学证据。近年来,循证疗法因其有可能改善个体患者的治疗效果,同时降低治疗成本而受到越来越多的关注并变得愈发重要。在临床实践中,几乎不可能跟上不断增加的文献数量,另一方面,也很难批判性地评估所呈现的数据。要发现研究设计中的系统偏差和其他错误,包括评估一项研究是否应成为个体治疗决策的一部分,需要扎实的科学和统计学知识以及大量的业余时间。因此,荟萃分析、综述和临床指南对于临床实践中的循证治疗越来越重要。本综述是关于治疗鼻塞和鼻窦炎的外部证据可得性的更新。显而易见,这两组疾病在外部证据的可得性方面存在显著差异。此外,很明显手术治疗方案通常所依据的证据质量明显低于药物治疗方案。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/753e/5169079/c40b428a96df/CTO-15-06-g-001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/753e/5169079/a429380efc73/CTO-15-06-t-001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/753e/5169079/1db89614e478/CTO-15-06-t-002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/753e/5169079/1d7a011a7205/CTO-15-06-t-003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/753e/5169079/2e8507447b01/CTO-15-06-t-004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/753e/5169079/cc6fbff576ff/CTO-15-06-t-005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/753e/5169079/c40b428a96df/CTO-15-06-g-001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/753e/5169079/a429380efc73/CTO-15-06-t-001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/753e/5169079/1db89614e478/CTO-15-06-t-002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/753e/5169079/1d7a011a7205/CTO-15-06-t-003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/753e/5169079/2e8507447b01/CTO-15-06-t-004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/753e/5169079/cc6fbff576ff/CTO-15-06-t-005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/753e/5169079/c40b428a96df/CTO-15-06-g-001.jpg

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