Trapp Judith, McAfee Alison, Foster Leonard J
Department of Biochemistry & Molecular Biology, Michael Smith Laboratories, University of British Columbia, 2125 East Mall, Vancouver, BC, V6T 1Z4, Canada.
Mol Ecol. 2017 Feb;26(3):718-739. doi: 10.1111/mec.13986. Epub 2017 Feb 1.
Globally, there are over 20 000 bee species (Hymenoptera: Apoidea: Anthophila) with a host of biologically fascinating characteristics. Although they have long been studied as models for social evolution, recent challenges to bee health (mainly diseases and pesticides) have gathered the attention of both public and research communities. Genome sequences of twelve bee species are now complete or under progress, facilitating the application of additional 'omic technologies. Here, we review recent developments in honey bee and native bee research in the genomic era. We discuss the progress in genome sequencing and functional annotation, followed by the enabled comparative genomics, proteomics and transcriptomics applications regarding social evolution and health. Finally, we end with comments on future challenges in the postgenomic era.
在全球范围内，有超过20000种蜜蜂（膜翅目：蜜蜂总科：花蜂），它们具有许多生物学上令人着迷的特征。尽管长期以来它们一直被作为社会进化的模型进行研究，但最近蜜蜂健康面临的挑战（主要是疾病和杀虫剂）引起了公众和研究界的关注。目前，12种蜜蜂的基因组序列已完成或正在进行中，这促进了其他“组学”技术的应用。在这里，我们回顾了基因组时代蜜蜂和本地蜜蜂研究的最新进展。我们讨论了基因组测序和功能注释方面的进展，随后是关于社会进化和健康的比较基因组学、蛋白质组学和转录组学应用。最后，我们对后基因组时代的未来挑战发表了评论。
