Pateisky N, Gitsch E
I. Universitäts-Frauenklinik Wien.
Arch Gynecol Obstet. 1989;245(1-4):606-9. doi: 10.1007/BF02417452.
The diagnostic possibilities of immunoscintigraphy (IS) in ovarian cancer are discussed. Seventy-five patients were investigated by IS using the radioantibodies HMFG-2 (n = 63) or OC-125 (n = 12). The results showed a specificity of 75%, sensitivity of 87%, and accuracy of 84%. An intraoperatively usable gamma ray detection probe was developed in order to achieve better results than with conventional IS. Twelve patients were investigated using this probe. A future clinical value was indicated for intraoperative detection of lymphnode metastases and/or small tumor deposits.
本文讨论了免疫闪烁成像(IS)在卵巢癌诊断中的可能性。使用放射性抗体HMFG - 2(n = 63)或OC - 125(n = 12)对75例患者进行了IS检查。结果显示特异性为75%,敏感性为87%,准确性为84%。为了获得比传统IS更好的结果,开发了一种术中可用的伽马射线检测探头。使用该探头对12例患者进行了检查。结果表明该探头在术中检测淋巴结转移和/或小肿瘤沉积物方面具有潜在的临床价值。