氧化亚氮镇静下内镜超声引导细针穿刺术用于消化道疾病的安全性和有效性的随机对照研究
Randomized controlled study of the safety and efficacy of nitrous oxide-sedated endoscopic ultrasound-guided fine needle aspiration for digestive tract diseases.
作者信息
Wang Cai-Xia, Wang Jian, Chen Yuan-Yuan, Wang Jia-Ni, Yu Xin, Yang Feng, Sun Si-Yu
机构信息
Cai-Xia Wang, Yuan-Yuan Chen, Jia-Ni Wang, Xin Yu, Feng Yang, Si-Yu Sun, Endoscopy Center, Shengjing Hospital of China Medical University, Shenyang 110004, Liaoning Province, China.
出版信息
World J Gastroenterol. 2016 Dec 14;22(46):10242-10248. doi: 10.3748/wjg.v22.i46.10242.
AIM
To evaluate the efficacy and safety of nitrous oxide-sedated endoscopic ultrasound-guided fine needle aspiration.
METHODS
Enrolled patients were divided randomly into an experimental group (inhalation of nitrous oxide) and a control group (inhalation of pure oxygen) and heart rate, blood oxygen saturation, blood pressure, electrocardiogram (ECG) changes, and the occurrence of complications were monitored and recorded. All patients and physicians completed satisfaction questionnaires about the examination and scored the process using a visual analog scale.
RESULTS
There was no significant difference in heart rate, blood oxygen saturation, blood pressure, ECG changes, or complication rate between the two groups of patients ( > 0.05). However, patient and physician satisfaction were both significantly higher in the nitrous oxide compared with the control group ( < 0.05).
CONCLUSION
Nitrous oxide-sedation is a safe and effective option for patients undergoing endoscopic ultrasound-guided fine needle aspiration.
目的
评估氧化亚氮镇静下内镜超声引导细针穿刺抽吸术的有效性和安全性。
方法
将入选患者随机分为实验组（吸入氧化亚氮）和对照组（吸入纯氧），监测并记录心率、血氧饱和度、血压、心电图（ECG）变化及并发症发生情况。所有患者和医生均完成关于检查的满意度问卷，并使用视觉模拟量表对过程进行评分。
结果
两组患者的心率、血氧饱和度、血压、心电图变化或并发症发生率无显著差异（>0.05）。然而，与对照组相比，氧化亚氮组患者和医生的满意度均显著更高（<0.05）。
结论
氧化亚氮镇静对于接受内镜超声引导细针穿刺抽吸术的患者是一种安全有效的选择。
Zotero 插件