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Surg Neurol Int. 2016 Nov 21;7(Suppl 38):S901-S904. doi: 10.4103/2152-7806.194515. eCollection 2016.
2
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本文引用的文献

1
Deadly falls: operative versus nonoperative management of Type II odontoid process fracture in octogenarians.致命性跌倒:老年患者Ⅱ型齿状突骨折的手术治疗与非手术治疗
J Neurosurg Spine. 2017 Jan;26(1):4-9. doi: 10.3171/2016.3.SPINE151202. Epub 2016 Aug 19.
2
Editorial: Management of Type II odontoid process fracture in octogenarians.社论:老年患者Ⅱ型齿状突骨折的治疗
J Neurosurg Spine. 2017 Jan;26(1):1-3. doi: 10.3171/2016.4.SPINE16333. Epub 2016 Aug 19.
3
Predictors of treatment outcomes in geriatric patients with odontoid fractures: AOSpine North America multi-centre prospective GOF study.老年齿状突骨折患者治疗结局的预测因素:AOSpine 北美多中心前瞻性 GOF 研究。
Spine (Phila Pa 1976). 2013 May 15;38(11):881-6. doi: 10.1097/BRS.0b013e31828314ee.
4
Anterior screw fixation of type IIB odontoid fractures in octogenarians.80 岁以上患者 IIB 型齿状突骨折的前路螺钉固定。
Eur Spine J. 2012 Feb;21(2):335-9. doi: 10.1007/s00586-011-2044-7. Epub 2011 Oct 19.
5
Impact of age, injury severity score, and medical comorbidities on early complications after fusion and halo-vest immobilization for C2 fractures in older adults: a propensity score matched retrospective cohort study.年龄、损伤严重程度评分和合并症对老年人 C2 骨折融合和 halo-vest 固定后早期并发症的影响:倾向评分匹配回顾性队列研究。
Spine (Phila Pa 1976). 2012 May 1;37(10):854-9. doi: 10.1097/BRS.0b013e3182377486.
6
Type II odontoid fractures of the cervical spine: do treatment type and medical comorbidities affect mortality in elderly patients?颈椎 II 型齿状突骨折:治疗类型和合并症是否会影响老年患者的死亡率?
Spine (Phila Pa 1976). 2011 May 15;36(11):879-85. doi: 10.1097/BRS.0b013e3181e8e77c.
7
Type II odontoid fractures in the elderly: an evidence-based narrative review of management.老年人 II 型齿状突骨折:基于证据的治疗叙述性综述。
Eur Spine J. 2011 Feb;20(2):195-204. doi: 10.1007/s00586-010-1507-6. Epub 2010 Sep 12.
8
Early complications of surgical versus conservative treatment of isolated type II odontoid fractures in octogenarians: a retrospective cohort study.老年患者孤立性Ⅱ型齿状突骨折手术与保守治疗的早期并发症:一项回顾性队列研究
J Spinal Disord Tech. 2008 Dec;21(8):535-9. doi: 10.1097/BSD.0b013e318163570b.
9
Posterior C1-C2 fusion with polyaxial screw and rod fixation.采用多轴螺钉和棒固定进行C1-C2后路融合术。
Spine (Phila Pa 1976). 2001 Nov 15;26(22):2467-71. doi: 10.1097/00007632-200111150-00014.
10
Odontoid fractures in elderly patients.老年患者的齿状突骨折
J Neurosurg. 1993 Jan;78(1):32-5. doi: 10.3171/jns.1993.78.1.0032.

八旬老人II型齿状突骨折的治疗评论:格拉费奥的文章及法拉维尼亚的社论(《神经外科脊柱杂志》2016年8月19日)

Commentary on the management of type II odontoid process fractures in octogenarians: Article by Graffeo . and Editorial by Falavigna (J Neurosurgery Spine August 19, 2016).

作者信息

Epstein Nancy E

机构信息

Department of Neuroscience, Winthrop Neuroscience, Winthrop University Hospital, Mineola, New York, USA.

出版信息

Surg Neurol Int. 2016 Nov 21;7(Suppl 38):S901-S904. doi: 10.4103/2152-7806.194515. eCollection 2016.

DOI:10.4103/2152-7806.194515
PMID:28028444
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5159695/
Abstract

BACKGROUND

Establishing a clear treatment paradigm for octogenarians with type II odontoid fractures in hampered by a literature replete with level III articles.

METHODS

In the study by Graffeo ., the authors evaluated 111 patients over the age of 79 (average age: 87) with type II odontoid fractures undergoing nonoperative (94 patients) vs. operative intervention (17 total; 15 posterior and 2 anterior). They studied multiple variables and utilized several scales [abbreviated injury scale (AIS), injury severity score (ISS), and the Glasgow coma scale (GCS)] to determine the outcomes of nonoperative vs. operative management.

RESULTS

Graffeo . concluded that there were no significant differences between nonoperative and operative management for type II odontoid fractures in octogenarians. They found similar frequencies of additional cervical fractures, mechanisms of injury, GCS of 8 or under, AIS/ISS scores, and disposition to "nonhome" facilities. Furthermore, both appeared to have increased mortality rates at 1-year post injury; 13% during hospitalization, 26% within the first post-injury month, and 41% at 1 year.

CONCLUSIONS

In the editorial by Falavigna, his major criticism of Graffeo's article was the marked disparity in the number of patients in the operative (17 patients) vs. the nonoperative group (94 patients), making it difficult to accept any conclusions as "significant". He further noted that few prior studies provided level I evidence, and that most, like this one, were level III analyses that did not "significantly" advance our knowledge as to whether to treat octogenarians with type II odontoid fractures operatively vs. nonoperatively.

摘要

背景

由于充斥着大量三级文献,为患有Ⅱ型齿状突骨折的八旬老人建立明确的治疗模式受到阻碍。

方法

在格拉菲奥等人的研究中,作者评估了111例79岁以上(平均年龄:87岁)的Ⅱ型齿状突骨折患者,其中94例接受非手术治疗,17例接受手术干预(15例后路手术,2例前路手术)。他们研究了多个变量,并使用了几种量表[简明损伤量表(AIS)、损伤严重程度评分(ISS)和格拉斯哥昏迷量表(GCS)]来确定非手术与手术治疗的结果。

结果

格拉菲奥等人得出结论,八旬老人Ⅱ型齿状突骨折的非手术治疗与手术治疗之间没有显著差异。他们发现额外颈椎骨折的发生率、损伤机制、GCS评分在8分及以下、AIS/ISS评分以及入住“非家庭”机构的情况相似。此外,两者在受伤后1年的死亡率似乎都有所上升;住院期间为13%,受伤后第一个月内为26%,1年后为41%。

结论

在法拉维尼亚的社论中,他对格拉菲奥文章的主要批评是手术组(17例患者)与非手术组(94例患者)的患者数量存在显著差异,这使得难以接受任何“显著”的结论。他进一步指出,很少有先前的研究提供一级证据,而且大多数研究,如本研究,都是三级分析,并没有“显著”推进我们对于八旬老人Ⅱ型齿状突骨折是进行手术治疗还是非手术治疗的认识。