Keith D J, de Berker D A R, Bray A P, Cheung S T, Brain A, Mohd Mustapa M F
British Association of Dermatologists, London, UK.
Clin Exp Dermatol. 2017 Jan;42(1):46-53. doi: 10.1111/ced.12990.
Diagnosis and management of nonmelanoma skin cancer (NMSC) represents a large part of the dermatology workload, and complete excision is a required surgical standard for treatment.
To conduct an audit of the surgical practice for the treatment of NMSC by dermatologists in the UK.
Data on 10 consecutive nonmicrographic excisions of nonmelanoma skin cancer by UK dermatologists. Data collected included site, preoperative diagnosis, histological diagnosis, proximity to previous scars, and histological deep and peripheral margins.
A total of 227 responses from 135 centres reported 2739 excisions. Excisions on the head and neck accounted for 58.3% of cases. Tumour diameter (mean ± SD) was 10.61 ± 6.9 mm (maximum 130 mm), and 96.7% of cases were primary excisions, with 3.3% being re-excisions. Basal cell carcinomas (BCCs) accounted for 79.1% (n = 2167) of the total cases and squamous cell carcinomas (SCCs) for 17.9% n = 491). Of the suspected BCCs and SCCS, 94.4% (n = 2045) and 66.8% (328), respectively, were confirmed histologically to be the respective carcinomas. Similar proportions of BCC and SCC cases were within 10 mm of a previous excision. Lateral and deep margins were clear in 98.3% and 99.2% of BCC cases, respectively, and in 98.4% and 97.1% of SCC cases, respectively. Reported surgical complication rate in the audit was 3.4%.
The majority of excisions for NMSC are for BCC and SCC. Our figures for diagnostic accuracy are at the upper range of previously published figures. Most patients were not followed up in secondary care, hence complication rates may be under-reported.
非黑色素瘤皮肤癌(NMSC)的诊断和管理在皮肤科工作量中占很大一部分,完整切除是治疗所需的手术标准。
对英国皮肤科医生治疗NMSC的手术实践进行审核。
收集英国皮肤科医生连续进行的10例非黑色素瘤皮肤癌非显微切除的数据。收集的数据包括部位、术前诊断、组织学诊断、与既往瘢痕的距离以及组织学深部和周边切缘。
来自135个中心的227份回复报告了2739例切除病例。头颈部切除病例占58.3%。肿瘤直径(均值±标准差)为10.61±6.9毫米(最大130毫米),96.7%的病例为初次切除,3.3%为再次切除。基底细胞癌(BCC)占总病例的79.1%(n = 2167),鳞状细胞癌(SCC)占17.9%(n = 491)。在疑似BCC和SCC中,分别有94.4%(n = 2045)和66.8%(328)经组织学确诊为相应的癌症。BCC和SCC病例中,与既往切除部位距离在10毫米以内的比例相似。BCC病例的外侧和深部切缘分别有98.3%和99.2%切缘清晰,SCC病例分别为98.4%和97.1%。审核中报告的手术并发症发生率为3.4%。
NMSC的大多数切除手术针对BCC和SCC。我们的诊断准确率数据处于先前发表数据的上限范围。大多数患者未在二级医疗中接受随访,因此并发症发生率可能报告不足。