Jannotta F S, Sidawy M K
Department of Pathology, George Washington University Medical Center, Washington, DC.
Arch Pathol Lab Med. 1989 Oct;113(10):1120-3.
In patients with the acquired immunodeficiency syndrome, mycobacterial lymphadenitis is characterized by the presence of numerous acid-fast bacilli within histiocytes. In Diff-Quik-stained cytologic preparations of such lymph nodes, performed during intraoperative consultations, the presence of mycobacteria is manifested by numerous negatively staining rod-shaped spaces intracellularly within histiocytes, as well as extra-cellularly in the background. Recognition of these characteristic "footprints," or "negative images," of mycobacteria can facilitate early diagnosis and treatment. The morphological characteristics that help to distinguish between Mycobacterium avium-intracellulare and Mycobacterium kansasii are also described.
在获得性免疫缺陷综合征患者中，分枝杆菌性淋巴结炎的特征是组织细胞内存在大量抗酸杆菌。在术中会诊时对这类淋巴结进行Diff - Quik染色的细胞涂片检查中，分枝杆菌的存在表现为组织细胞内大量细胞内阴性染色的杆状空隙，以及背景中的细胞外空隙。识别这些分枝杆菌的特征性“足迹”或“负像”有助于早期诊断和治疗。文中还描述了有助于区分鸟分枝杆菌复合群和堪萨斯分枝杆菌的形态学特征。
