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肺出血作为呼吸道合胞病毒(RSV)细支气管炎的一种并发症。

Pulmonary hemorrhage as a complication of Respiratory Syncyntial Virus (RSV) bronchiolitis.

作者信息

Soo Audrey K S, Inwald David P

机构信息

Imperial College Healthcare NHS Trust, London, United Kingdom.

出版信息

Pediatr Pulmonol. 2017 Jun;52(6):E32-E36. doi: 10.1002/ppul.23637. Epub 2016 Dec 28.

DOI:10.1002/ppul.23637
PMID:28029754
Abstract

Respiratory Syncytial Virus (RSV) is a common cause of bronchiolitis. Although there are a number of recognized complications, pulmonary hemorrhage has not been reported previously. A retrospective case notes review was performed through an electronic search of a Pediatric Intensive Care Unit's medical records. Seven patients with RSV infection and pulmonary hemorrhage were identified and included in this case series. Six of the seven patients were born prematurely (30-36 weeks gestation). All patients required blood transfusion. The pulmonary hemorrhage events all occurred after a period of mechanical ventilation and following extubation. All of the patients required reintubation with a mean of 5 further days of mechanical ventilation. Pulmonary hemorrhage is an uncommon complication of RSV infection, which has not been reported previously in the literature. Further studies are required to determine incidence, pathogenesis, and outcome. Pediatr Pulmonol. 2017;52:E32-E36. © 2016 Wiley Periodicals, Inc.

摘要

呼吸道合胞病毒(RSV)是细支气管炎的常见病因。尽管存在一些公认的并发症,但此前尚未有肺出血的报道。通过对儿科重症监护病房的病历进行电子检索,开展了一项回顾性病例记录审查。确定了7例RSV感染合并肺出血的患者并纳入本病例系列。7例患者中有6例为早产儿(妊娠30 - 36周)。所有患者均需要输血。肺出血事件均发生在一段时间的机械通气及拔管之后。所有患者均需要再次插管,平均还需要5天的机械通气。肺出血是RSV感染的一种罕见并发症,此前文献中未见报道。需要进一步研究以确定其发病率、发病机制及转归。《儿科肺科杂志》。2017年;52卷:E32 - E36。© 2016威利期刊公司

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